Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Penile Induration D010411 4 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Lung Neoplasms D008175 171 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Glioma D005910 112 associated lipids
Gastritis D005756 27 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Brain Ischemia D002545 89 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma D002277 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Lee SO et al. Wogonin suppresses TNF-alpha-induced MMP-9 expression by blocking the NF-kappaB activation via MAPK signaling pathways in human aortic smooth muscle cells. 2006 Biochem. Biophys. Res. Commun. pmid:17052690
Wang W et al. The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo. 2006 Biol. Pharm. Bull. pmid:16755005
Feng YL et al. [Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography]. 2006 Yao Xue Xue Bao pmid:16759005
Chang WT et al. Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. 2006 Am. J. Chin. Med. pmid:16700106
Shen SC et al. Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. 2006 Neuroscience pmid:16580779
Pan MH et al. Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. 2006 Biochem. Pharmacol. pmid:16949556
Hu Y et al. Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. 2006 Biochem. Biophys. Res. Commun. pmid:17069758
Zhang H et al. Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. 2006 J Chromatogr A pmid:16952364
Kim YH et al. Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. 2006 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:16893689
Zhao Y et al. Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. 2006 Eur. J. Pharmacol. pmid:16574098