Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Carcinoma D002277 18 associated lipids
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Glioma D005910 112 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Brain Ischemia D002545 89 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Papillomavirus Infections D030361 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Shih YT et al. San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. 2011 Evid Based Complement Alternat Med pmid:19339484
Li C et al. Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. 2011 J Pharm Biomed Anal pmid:21051171
Lim H et al. Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways. 2011 J. Pharmacol. Sci. pmid:21606625
Ahn SH et al. Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. 2011 BMC Neurosci pmid:21810275
Tan W et al. Anti-cancer natural products isolated from chinese medicinal herbs. 2011 Chin Med pmid:21777476
Chen J et al. Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. 2011 Biomed. Chromatogr. pmid:21154891
Zan B et al. Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. 2011 Biomed. Chromatogr. pmid:20872909
Takahashi H et al. Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. 2011 Biochim. Biophys. Acta pmid:21596068
Yu JS and Kim AK Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. 2011 Mol. Cells pmid:21448585
Zhao L et al. Developmental toxicity and genotoxicity studies of wogonin. 2011 Regul. Toxicol. Pharmacol. pmid:21459121
Chen P et al. Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. 2011 Toxicology pmid:21295103
Yang L et al. Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. 2011 Cancer Sci. pmid:21244577
Chow SE et al. Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. 2011 Cancer Chemother. Pharmacol. pmid:21207227
Chen CY et al. Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. 2011 J. Nutr. Biochem. pmid:21190831
Messaoudene D et al. Ex vivo effects of flavonoïds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behçet's disease. 2011 J Inflamm (Lond) pmid:22104639
Su SY and Hsieh CL Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. 2011 Chin Med pmid:21740583
Petraglia AL et al. Stuck at the bench: Potential natural neuroprotective compounds for concussion. 2011 Surg Neurol Int pmid:22059141
Samarghandian S et al. Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. 2011 Clinics (Sao Paulo) pmid:21808878
Hou YC et al. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. 2011 Planta Med. pmid:20957598
Lee MY et al. A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. 2011 Toxicol Int pmid:21976821