Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Xu X et al. | Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway. | 2014 | Biochem. Pharmacol. | pmid:25264278 |
Lee W et al. | Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. | 2015 | Inflammation | pmid:25249339 |
Marsh Z et al. | Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. | 2014 | Phytochemistry | pmid:25236693 |
Kwak S et al. | Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. | 2014 | Toxicol. Appl. Pharmacol. | pmid:25223693 |
Zhao K et al. | Wogonin suppresses melanoma cell B16-F10 invasion and migration by inhibiting Ras-medicated pathways. | 2014 | PLoS ONE | pmid:25203554 |
Hosseinzadeh Z et al. | Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25168590 |
Yang H et al. | Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells. | 2014 | Oncotarget | pmid:25149543 |
Huang KF et al. | [Experimental study on inhibitory effect of wogonin on proliferation and invasion of breast cancer cells]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:25039187 |
Nam KW et al. | The role of wogonin in controlling SOCS3 expression in neuronal cells. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25035930 |
Ku SK and Bae JS | Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. | 2014 | Fitoterapia | pmid:25020199 |