Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Papillomavirus Infections D030361 4 associated lipids
Penile Induration D010411 4 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Carcinoma D002277 18 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Breast Neoplasms D001943 24 associated lipids
Gastritis D005756 27 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Acute Lung Injury D055371 33 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Leukemia D007938 74 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Li C et al. Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact. 2014 Pharm Biol pmid:24102566
Tian SS et al. Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis. 2014 Fitoterapia pmid:24096161
Xu F et al. The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters. 2013 J Pharm Sci pmid:24018852
Chirumbolo S Anticancer properties of the flavone wogonin. 2013 Toxicology pmid:23994129
Kim MS et al. Wogonin induces apoptosis by suppressing E6 and E7 expressions and activating intrinsic signaling pathways in HPV-16 cervical cancer cells. 2013 Cell Biol. Toxicol. pmid:23955116
He L et al. Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. 2013 Toxicology pmid:23907061
Wang Y et al. GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. 2013 Toxicol. Lett. pmid:23872260
Attia SM et al. Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. 2013 Food Chem. Toxicol. pmid:23872129
Zhao L et al. Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. 2013 Biochem. Cell Biol. pmid:23859016
Zhang Y et al. V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma. 2014 Arch. Toxicol. pmid:23835921