Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chang WH et al. | Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. | 2002 | Planta Med. | pmid:11859462 |
Ma SC et al. | Antiviral Chinese medicinal herbs against respiratory syncytial virus. | 2002 | J Ethnopharmacol | pmid:11801383 |
Lee WR et al. | Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. | 2002 | Biochem. Pharmacol. | pmid:11841797 |
Lai MY et al. | Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. | 2003 | Biol. Pharm. Bull. | pmid:12520178 |
Huang WH et al. | Novel synthesis of flavonoids of Scutellaria baicalensis Georgi. | 2003 | Chem. Pharm. Bull. | pmid:12612426 |
Lee H et al. | Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. | 2003 | FASEB J. | pmid:12897065 |
Li DR et al. | [Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]. | 2003 | Ai Zheng | pmid:12917023 |
Chi YS et al. | Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression. | 2003 | Biochem. Pharmacol. | pmid:14505806 |
Wang Z et al. | Wogonin suppresses cellular proliferation and expression of monocyte chemoattractant protein 1 in Peyronie's plaque-derived cells. | 2003 | BJU Int. | pmid:14616461 |
Pal M et al. | Antifungal activity of wogonin. | 2003 | Phytother Res | pmid:14669259 |