Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Oshima N et al. | Quantitative analysis of anti-inflammatory activity of orengedokuto: importance of combination of flavonoids in inhibition of PGE2 production in mouse macrophage-like cell line J774.1. | 2013 | J Nat Med | pmid:22729955 |
Yu C et al. | Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis. | 2013 | Pharm Biol | pmid:23738852 |
Wang Y et al. | GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. | 2013 | Toxicol. Lett. | pmid:23872260 |
Zhao L et al. | Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. | 2013 | Biochem. Cell Biol. | pmid:23859016 |
Wang F et al. | Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. | 2013 | Toxicology | pmid:23246481 |
Kim MS et al. | Wogonin induces apoptosis by suppressing E6 and E7 expressions and activating intrinsic signaling pathways in HPV-16 cervical cancer cells. | 2013 | Cell Biol. Toxicol. | pmid:23955116 |
Attia SM et al. | Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. | 2013 | Food Chem. Toxicol. | pmid:23872129 |
Ci X et al. | Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury. | 2012 | PLoS ONE | pmid:22563373 |
Li HY et al. | Comparative study of the effect of baicalin and its natural analogs on neurons with oxygen and glucose deprivation involving innate immune reaction of TLR2/TNFα. | 2012 | J. Biomed. Biotechnol. | pmid:22536016 |
Koppula S et al. | Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. | 2012 | Mediators Inflamm. | pmid:22577256 |