Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chengcheng G et al. | Probe substrate and enzyme source-dependent inhibition of UDP-glucuronosyltransferase (UGT) 1A9 by wogonin. | 2013 | Afr Health Sci | pmid:24250287 |
Li DR et al. | [Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]. | 2003 | Ai Zheng | pmid:12917023 |
Aung H et al. | Scutellaria baicalensis decreases ritonavir-induced nausea. | 2005 | AIDS Res Ther | pmid:16368007 |
Ryu NH et al. | Wogonin inhibits transforming growth factor β1-induced extracellular matrix production via the p38/activator protein 1 signaling pathway in nasal polyp-derived fibroblasts. | 2016 | Am J Rhinol Allergy | pmid:27456588 |
Chang WT et al. | Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. | 2006 | Am. J. Chin. Med. | pmid:16700106 |
Lin CM et al. | Functional role of wogonin in anti-angiogenesis. | 2012 | Am. J. Chin. Med. | pmid:22419433 |
Hayasaka S et al. | Traditional Japanese herbal (kampo) medicines and treatment of ocular diseases: a review. | 2012 | Am. J. Chin. Med. | pmid:22928823 |
Chen CY et al. | Comparative chemical and statistical analysis of cultivated and wild Radix Scutellariae. | 2011 | Am. J. Chin. Med. | pmid:21905290 |
Lin CC and Shieh DE | The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. | 1996 | Am. J. Chin. Med. | pmid:8739179 |
Nakahata N et al. | Analysis of inhibitory effects of scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells. | 1998 | Am. J. Chin. Med. | pmid:9862019 |