Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Wogonin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Li C et al. | Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. | 2011 | J Pharm Biomed Anal | pmid:21051171 |
Lim H et al. | Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways. | 2011 | J. Pharmacol. Sci. | pmid:21606625 |
Mazzio EA et al. | The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | 2011 | Int J Mol Sci | pmid:21340000 |
Tan W et al. | Anti-cancer natural products isolated from chinese medicinal herbs. | 2011 | Chin Med | pmid:21777476 |
Chen J et al. | Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. | 2011 | Biomed. Chromatogr. | pmid:21154891 |
Zan B et al. | Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. | 2011 | Biomed. Chromatogr. | pmid:20872909 |
Takahashi H et al. | Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. | 2011 | Biochim. Biophys. Acta | pmid:21596068 |
Jeong JC et al. | Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21501525 |
Tang H et al. | The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells. | 2011 | BMC Biol. | pmid:21418589 |
Enomoto R et al. | Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. | 2011 | Cancer Chemother. Pharmacol. | pmid:20658136 |
Su SY and Hsieh CL | Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. | 2011 | Chin Med | pmid:21740583 |
Hou YC et al. | Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. | 2011 | Planta Med. | pmid:20957598 |
Ha SK et al. | 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. | 2012 | Neuropharmacology | pmid:22465818 |
Li Y et al. | Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22560901 |
Li WJ et al. | Phenolic compounds and antioxidant activities of Liriope muscari. | 2012 | Molecules | pmid:22328078 |
Matsunaga T et al. | Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. | 2012 | Front Pharmacol | pmid:22319498 |
Ho FM et al. | Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. | 2012 | J Ethnopharmacol | pmid:22543166 |
Wilczańska-Barska A et al. | Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. | 2012 | Biotechnol. Lett. | pmid:22639092 |
Eylenstein A et al. | Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions. | 2012 | J. Biol. Chem. | pmid:22110130 |
Chi DS et al. | Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. | 2012 | Clin Mol Allergy | pmid:22309647 |