Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Carcinoma D002277 18 associated lipids
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Glioma D005910 112 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Brain Ischemia D002545 89 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Penile Induration D010411 4 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Cao H et al. Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. 2009 J. Hazard. Mater. pmid:19577841
Ding XF et al. [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. 2009 Guang Pu Xue Yu Guang Pu Fen Xi pmid:19650472
Lee DH et al. Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. 2009 Br. J. Pharmacol. pmid:19438509
Yang L et al. Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. 2009 Biochem. Cell Biol. pmid:19935879
Li J et al. Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. 2009 J. Nat. Prod. pmid:19555121
Gurung SK et al. Inhibition of prostaglandin E2 production by synthetic wogonin analogs. 2009 Arch. Pharm. Res. pmid:20091262
Kaneko T et al. Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. 2009 Jul-Aug In Vivo pmid:19567393
Lu B et al. Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. 2009 Sep-Oct Phytochem Anal pmid:19533595
Lin CW et al. 12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. 2010 J. Cell. Physiol. pmid:20458747
Ni Y et al. Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches. 2010 Anal. Chim. Acta pmid:20206002
Wang CZ et al. Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. 2010 Phytomedicine pmid:19836937
Ye G et al. Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. 2010 Chem. Biodivers. pmid:21162005
Li Y et al. Combinative method using HPLC fingerprint and quantitative analyses for quality consistency evaluation of an herbal medicinal preparation produced by different manufacturers. 2010 J Pharm Biomed Anal pmid:20138726
Wei L et al. Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. 2010 J. Cell. Biochem. pmid:21053277
Lim JS et al. Wogonin induces differentiation and neurite outgrowth of neural precursor cells. 2010 Biochem. Biophys. Res. Commun. pmid:20888794
Lei W et al. Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. 2010 Genet. Mol. Biol. pmid:21637484
Xu H et al. Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. 2010 Bioresour. Technol. pmid:20708926
Schrader KK Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). 2010 Toxins (Basel) pmid:22069655
Gao J et al. Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. 2010 J Pharm Biomed Anal pmid:20457505
Feng J et al. Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. 2010 J Pharm Biomed Anal pmid:20430560