Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lin CM et al. | Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1. | 2006 | Int. Immunopharmacol. | pmid:16979123 |
| Wang W et al. | Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. | 2006 | Anticancer Drugs | pmid:16926629 |
| Fas SC et al. | Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis. | 2006 | Blood | pmid:16931628 |
| Chang WT et al. | Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. | 2006 | Am. J. Chin. Med. | pmid:16700106 |
| Shen SC et al. | Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. | 2006 | Neuroscience | pmid:16580779 |
| Adams LS et al. | Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. | 2006 | Evid Based Complement Alternat Med | pmid:16550232 |
| Pan MH et al. | Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. | 2006 | Biochem. Pharmacol. | pmid:16949556 |
| Chang LC and Sun SW | Micellar electrokinetic chromatography for separation of a mixture of coptis alkaloids, scute flavonoids, and rhubarb anthraquinones and bianthrones. | 2006 | J Pharm Biomed Anal | pmid:16297588 |
| Hu Y et al. | Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17069758 |
| Huang WH et al. | Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI. | 2006 | Biosci. Biotechnol. Biochem. | pmid:17031041 |
| Zhang H et al. | Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. | 2006 | J Chromatogr A | pmid:16952364 |
| Zgórka G | Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus. | 2006 | J Chromatogr A | pmid:16364344 |
| Kim YH et al. | Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. | 2006 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:16893689 |
| Zhao Y et al. | Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. | 2006 | Eur. J. Pharmacol. | pmid:16574098 |
| Tang NY et al. | Effects of wogonin on the levels of cytokines and functions of leukocytes associated with NF-kappa B expression in Sprague-Dawley rats. | 2006 Jul-Aug | In Vivo | pmid:16900784 |
| Enomoto R et al. | Wogonin prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17404053 |
| Lee E et al. | Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17404065 |
| Guo Q et al. | Anti-hepatitis B virus activity of wogonin in vitro and in vivo. | 2007 | Antiviral Res. | pmid:17280723 |
| Lee BS et al. | Wogonin suppresses TARC expression induced by mite antigen via heme oxygenase 1 in human keratinocytes. Suppressive effect of wogonin on mite antigen-induced TARC expression. | 2007 | J. Dermatol. Sci. | pmid:17317108 |
| Enomoto R et al. | Wogonin prevents glucocorticoid-induced thymocyte apoptosis without diminishing its anti-inflammatory action. | 2007 | J. Pharmacol. Sci. | pmid:17690528 |