| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chang WT et al. | Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. | 2007 | Eur. J. Pharmacol. | pmid:17475241 |
| Park BK et al. | Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. | 2001 | Eur. J. Pharmacol. | pmid:11502282 |
| Toton E et al. | The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease. | 2012 | Eur. J. Pharmacol. | pmid:22381066 |
| Shen SC et al. | In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. | 2002 | Eur. J. Pharmacol. | pmid:12098601 |
| Wakabayashi I and Yasui K | Wogonin inhibits inducible prostaglandin E(2) production in macrophages. | 2000 | Eur. J. Pharmacol. | pmid:11040356 |
| Kimura Y and Sumiyoshi M | Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. | 2011 | Eur. J. Pharmacol. | pmid:21549115 |
| Cho J and Lee HK | Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. | 2004 | Eur. J. Pharmacol. | pmid:14757129 |
| Zhao Y et al. | Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. | 2006 | Eur. J. Pharmacol. | pmid:16574098 |
| Huang HC et al. | Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell. | 1994 | Eur. J. Pharmacol. | pmid:8137874 |
| Ohtake N et al. | The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. | 2005 | Eur. J. Pharmacol. | pmid:15659321 |
| Park HG et al. | Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis. | 2007 | Eur. J. Pharmacol. | pmid:17692312 |
| Li Y and Martin RC | Herbal medicine and hepatocellular carcinoma: applications and challenges. | 2011 | Evid Based Complement Alternat Med | pmid:21799681 |
| Shih YT et al. | San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. | 2011 | Evid Based Complement Alternat Med | pmid:19339484 |
| Adams LS et al. | Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. | 2006 | Evid Based Complement Alternat Med | pmid:16550232 |
| Li X et al. | Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. | 2012 | Evid Based Complement Alternat Med | pmid:22235229 |
| Qi XF et al. | Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. | 2012 | Evid Based Complement Alternat Med | pmid:21785648 |
| Tayarani-Najaran Z et al. | Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. | 2011 | Evid Based Complement Alternat Med | pmid:20028719 |
| Im AR et al. | Scutellaria baicalensis Extracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction. | 2012 | Evid Based Complement Alternat Med | pmid:22969827 |
| Pan SY et al. | New perspectives on chinese herbal medicine (zhong-yao) research and development. | 2011 | Evid Based Complement Alternat Med | pmid:21785622 |
| Zhang N et al. | A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. | 2012 | Evid Based Complement Alternat Med | pmid:22272213 |