Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Leukemia D007938 74 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Penile Induration D010411 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Sarcoma 180 D012510 21 associated lipids
Translocation, Genetic D014178 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Chen S et al. Down-regulation of androgen-receptor and PSA by phytochemicals. 2008 Int. J. Oncol. pmid:18202763
Li YQ et al. Two new alkaloids from Capparis himalayensis. 2008 Chem. Pharm. Bull. pmid:18239306
Coleta M et al. Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity. 2008 Behav. Brain Res. pmid:18249450
Kauss T et al. Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis. 2008 Arthritis Res. Ther. pmid:18252009
Hämäläinen M et al. Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. 2007 Mediators Inflamm. pmid:18274639
Lee CY et al. Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. 2008 Liver Int. pmid:18346132
Zhang K et al. Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. 2008 Cancer Sci. pmid:18377421
Lee DH et al. Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. 2008 Biochem. Pharmacol. pmid:18377871
Lu N et al. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. 2008 Life Sci. pmid:18378261
Makino T et al. Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products. 2008 J Nat Med pmid:18404307