| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ueng YF et al. | Protective effects of baicalein and wogonin against benzo[a]pyrene- and aflatoxin B(1)-induced genotoxicities. | 2001 | Biochem. Pharmacol. | pmid:11755119 |
| Chen YC et al. | Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. | 2001 | Biochem. Pharmacol. | pmid:11331078 |
| Lee DH et al. | Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. | 2008 | Biochem. Pharmacol. | pmid:18377871 |
| Pan MH et al. | Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. | 2006 | Biochem. Pharmacol. | pmid:16949556 |
| Lee WR et al. | Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. | 2002 | Biochem. Pharmacol. | pmid:11841797 |
| Chi YS et al. | Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells. | 2001 | Biochem. Pharmacol. | pmid:11322923 |
| Chen F et al. | Reversal of cisplatin resistance in human gastric cancer cells by a wogonin-conjugated Pt(IV) prodrug via attenuating Casein Kinase 2-mediated Nuclear Factor-κB pathways. | 2017 | Biochem. Pharmacol. | pmid:28288821 |
| Xu X et al. | Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway. | 2014 | Biochem. Pharmacol. | pmid:25264278 |
| Gao Z et al. | Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. | 1999 | Biochim. Biophys. Acta | pmid:10564778 |
| Takahashi H et al. | Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. | 2011 | Biochim. Biophys. Acta | pmid:21596068 |
| Lin YT et al. | Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. | 2003 | Biol. Pharm. Bull. | pmid:12736527 |
| Wang W et al. | The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo. | 2006 | Biol. Pharm. Bull. | pmid:16755005 |
| Zuo F et al. | Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. | 2003 | Biol. Pharm. Bull. | pmid:12843610 |
| Zuo F et al. | Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora. | 2002 | Biol. Pharm. Bull. | pmid:12033492 |
| Liu ZL et al. | Induction of apoptosis in human lung fibroblasts and peripheral lymphocytes in vitro by Shosaiko-to derived phenolic metabolites. | 2002 | Biol. Pharm. Bull. | pmid:11824553 |
| Zuo F et al. | Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography. | 2001 | Biol. Pharm. Bull. | pmid:11411561 |
| Han CK et al. | Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism. | 2005 | Biol. Pharm. Bull. | pmid:16079475 |
| Qu JT et al. | Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study. | 2015 | Biol. Pharm. Bull. | pmid:26632179 |
| Kasai A et al. | Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. | 2008 | Biol. Pharm. Bull. | pmid:18451504 |
| Cho J and Lee HK | Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. | 2004 | Biol. Pharm. Bull. | pmid:15467195 |