Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Leukemia D007938 74 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Penile Induration D010411 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Sarcoma 180 D012510 21 associated lipids
Translocation, Genetic D014178 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Zuo F et al. Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora. 2002 Biol. Pharm. Bull. pmid:12033492
Ruibin J et al. Therapy Effects of Wogonin on Ovarian Cancer Cells. 2017 Biomed Res Int pmid:29181409
Li C et al. Non-aqueous capillary electrophoresis for simultaneous separation and determination of three major active components in traditional medicinal preparations. 2005 Biomed. Chromatogr. pmid:15627280
Chen M et al. Simultaneous determination of wogonin, oroxylin a, schisandrin, paeoniflorin and emodin in rat serum by HPLC-MS/MS and application to pharmacokinetic studies. 2017 Biomed. Chromatogr. pmid:28236316
Zhang YY et al. Comparative study of Scutellaria planipes and Scutellaria baicalensis. 1998 Jan-Feb Biomed. Chromatogr. pmid:9470972
Chen J et al. Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. 2011 Biomed. Chromatogr. pmid:21154891
Zan B et al. Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. 2011 Biomed. Chromatogr. pmid:20872909
Chen J et al. Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. 2017 Biomed. Pharmacother. pmid:28486193
Tian J et al. Interaction of wogonin with bovine serum albumin. 2005 Bioorg. Med. Chem. pmid:15911327
Qin X et al. Novel platinum(IV) complexes conjugated with a wogonin derivative as multi-targeted anticancer agents. 2017 Bioorg. Med. Chem. pmid:28314511
Pham TA et al. Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production. 2012 Bioorg. Med. Chem. Lett. pmid:22366656
Tran TD et al. Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. 2009 Bioorg. Med. Chem. Lett. pmid:19233646
Bian J et al. Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents. 2017 Bioorg. Med. Chem. Lett. pmid:28117202
Li C et al. Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones. 2011 Biopharm Drug Dispos pmid:21928297
Xu H et al. Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. 2010 Bioresour. Technol. pmid:20708926
Cui X et al. Traditional Chinese medicine and related active compounds against hepatitis B virus infection. 2010 Biosci Trends pmid:20448340
Yamashita Y et al. Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation. 2017 Biosci. Biotechnol. Biochem. pmid:28345416
Huang WH et al. Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI. 2006 Biosci. Biotechnol. Biochem. pmid:17031041
Lim BO et al. Effect of the flavonoid components obtained from Scutellaria radix on the histamine, immunoglobulin E and lipid peroxidation of spleen lymphocytes of Sprague-Dawley rats. 2003 Biosci. Biotechnol. Biochem. pmid:12834292
Lim BO Efficacy of wogonin in the production of immunoglobulins and cytokines by mesenteric lymph node lymphocytes in mouse colitis induced with dextran sulfate sodium. 2004 Biosci. Biotechnol. Biochem. pmid:15618621