Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Ni Y et al. Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches. 2010 Anal. Chim. Acta pmid:20206002
Li Y et al. Combinative method using HPLC fingerprint and quantitative analyses for quality consistency evaluation of an herbal medicinal preparation produced by different manufacturers. 2010 J Pharm Biomed Anal pmid:20138726
You J et al. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. 2010 J Chromatogr A pmid:20138285
Kaneko T et al. Inhibition of prostaglandin E2 production by flavone and its related compounds. In Vivo pmid:20133976
Gurung SK et al. Inhibition of prostaglandin E2 production by synthetic wogonin analogs. 2009 Arch. Pharm. Res. pmid:20091262
Kim HS et al. Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. 2009 J. Microbiol. Biotechnol. pmid:20075633
Tayarani-Najaran Z et al. Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. 2011 Evid Based Complement Alternat Med pmid:20028719
Chen B et al. Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. 2009 Int J Nanomedicine pmid:20011242
Jang S et al. Wogonin inhibits osteoclast formation induced by lipopolysaccharide. 2010 Phytother Res pmid:19998398
Yang L et al. Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. 2009 Biochem. Cell Biol. pmid:19935879
Ishii K et al. Effects of naturally occurring polymethyoxyflavonoids on cell growth, p-glycoprotein function, cell cycle, and apoptosis of daunorubicin-resistant T lymphoblastoid leukemia cells. 2010 Cancer Invest. pmid:19863351
Wang CZ et al. Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. 2010 Phytomedicine pmid:19836937
Zhou XQ et al. [Flavonoids from Scutellaria baicalensis and their bioactivities]. 2009 Beijing Da Xue Xue Bao pmid:19829679
Willimott S et al. An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. 2009 Chem Cent J pmid:19785738
Liang X et al. Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. 2010 J Pharm Biomed Anal pmid:19783115
Shia CS et al. Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. 2011 Evid Based Complement Alternat Med pmid:19737807
Lee E et al. Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. 2009 Ann. N. Y. Acad. Sci. pmid:19723047
Calvo TR et al. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. 2011 Evid Based Complement Alternat Med pmid:19696193
Rushworth SA and Micheau O Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer. 2009 Br. J. Pharmacol. pmid:19664138
Ding XF et al. [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. 2009 Guang Pu Xue Yu Guang Pu Fen Xi pmid:19650472