MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shu Q et al. | Wogonin induces retinal neuron-like differentiation of bone marrow stem cells by inhibiting Notch-1 signaling. | 2017 | Oncotarget | pmid:28415701 |
Paudel MK et al. | The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide. | 2017 | J. Biotechnol. | pmid:28392422 |
Wei CY et al. | Protective effect of wogonin on endotoxin-induced acute lung injury via reduction of p38 MAPK and JNK phosphorylation. | 2017 | Environ. Toxicol. | pmid:26892447 |
Zhao Q et al. | Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4'-Deoxyflavones in Scutellaria baicalensis. | 2018 | Mol Plant | pmid:28842248 |
Hong M et al. | Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. | 2018 | Molecules | pmid:29439451 |
Hong ZP et al. | Wogonin exacerbates the cytotoxic effect of oxaliplatin by inducing nitrosative stress and autophagy in human gastric cancer cells. | 2018 | Phytomedicine | pmid:29433678 |
Shimizu T et al. | Synergistic effect of baicalein, wogonin and oroxylin A mixture: multistep inhibition of the NF-κB signalling pathway contributes to an anti-inflammatory effect of Scutellaria root flavonoids. | 2018 | J Nat Med | pmid:28921127 |
Sukkar B et al. | Inhibition of Lithium Sensitive Orai1/ STIM1 Expression and Store Operated Ca2+ Entry in Chorea-Acanthocytosis Neurons by NF-κB Inhibitor Wogonin. | 2018 | Cell. Physiol. Biochem. | pmid:30453283 |
Wang CZ et al. | Deglycosylation of wogonoside enhances its anticancer potential. | 2018 | J Cancer Res Ther | pmid:30249874 |
Go JH et al. | Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade. | 2018 | Int. J. Mol. Med. | pmid:30015917 |
Sabra SA et al. | Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer. | 2018 | Eur J Pharm Biopharm | pmid:29689288 |
Xu PP et al. | Wogonin Inhibits Growth of Mantle Cell Lymphoma Cells through Nuclear Factor-κB Signaling Pathway. | 2018 | Chin. Med. J. | pmid:29451160 |
Meng XM et al. | Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis. | 2018 | Lab. Invest. | pmid:29200200 |
Zhao K et al. | LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. | 2018 | Gene | pmid:29196258 |
Zhang Y et al. | The Influence of Compatibility of Rhubarb and Radix Scutellariae on the Pharmacokinetics of Anthraquinones and Flavonoids in Rat Plasma. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29134502 |