MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Huynh DL et al. | Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression. | 2017 | BMC Complement Altern Med | pmid:28606135 |
Chen J et al. | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Biomed. Pharmacother. | pmid:28486193 |
Fong SYK et al. | Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice. | 2017 | Mol. Pharm. | pmid:28426226 |
Shu Q et al. | Wogonin induces retinal neuron-like differentiation of bone marrow stem cells by inhibiting Notch-1 signaling. | 2017 | Oncotarget | pmid:28415701 |
Paudel MK et al. | The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide. | 2017 | J. Biotechnol. | pmid:28392422 |
Yamashita Y et al. | Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28345416 |
Shi G et al. | Response of human non-small-cell lung cancer cells to the influence of Wogonin with SGK1 dynamics. | 2017 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:28338770 |
Qin X et al. | Novel platinum(IV) complexes conjugated with a wogonin derivative as multi-targeted anticancer agents. | 2017 | Bioorg. Med. Chem. | pmid:28314511 |
Chen F et al. | Reversal of cisplatin resistance in human gastric cancer cells by a wogonin-conjugated Pt(IV) prodrug via attenuating Casein Kinase 2-mediated Nuclear Factor-κB pathways. | 2017 | Biochem. Pharmacol. | pmid:28288821 |
Liu RX et al. | Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis. | 2017 | Chin J Nat Med | pmid:28284428 |