MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Woźniak D et al. | Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix. | 2015 | Nat. Prod. Res. | pmid:25427178 |
Liu J et al. | Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression. | 2015 | PLoS ONE | pmid:26317778 |
Ku SK and Bae JS | Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. | 2015 | BMB Rep | pmid:25739393 |
Lu H et al. | Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis. | 2015 | Mol Med Rep | pmid:26398525 |
Zhang YM et al. | Wogonin suppresses osteopontin expression in adipocytes by activating PPARα. | 2015 | Acta Pharmacol. Sin. | pmid:26073326 |
Lee JY and Park W | Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. | 2015 | Molecules | pmid:25913928 |
Boozari M et al. | Growth inhibition and apoptosis induction by Scutellaria pinnatifida A. Ham. on HL-60 and K562 leukemic cell lines. | 2015 | Environ. Toxicol. Pharmacol. | pmid:25546119 |
Chen S et al. | Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway. | 2015 | Cell. Mol. Neurobiol. | pmid:25504431 |
Chen F et al. | Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway. | 2015 | J. Mol. Neurosci. | pmid:25417142 |
Xu S et al. | Wogonin prevents rat dorsal root ganglion neurons death via inhibiting tunicamycin-induced ER stress in vitro. | 2015 | Cell. Mol. Neurobiol. | pmid:25381475 |