MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhao L et al. | LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells. | 2016 | Mol. Carcinog. | pmid:25945460 |
Wang W et al. | Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. | 2015 | Inflamm. Res. | pmid:25917044 |
Lee JY and Park W | Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. | 2015 | Molecules | pmid:25913928 |
Hu C et al. | Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway. | 2015 | Oncol. Rep. | pmid:25846394 |
Persson C | Drug-induced death of eosinophils. Promises and pitfalls. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25767918 |
Ge W et al. | Wogonin Induced Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Human Malignant Neuroblastoma Cells Via IRE1α-Dependent Pathway. | 2015 | J. Mol. Neurosci. | pmid:25740014 |
Ku SK and Bae JS | Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. | 2015 | BMB Rep | pmid:25739393 |
Dong LL et al. | An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix. | 2012 | Food Chem | pmid:25683416 |
Tan CX et al. | Activities of wogonin analogs and other flavones against Flavobacterium columnare. | 2015 | Chem. Biodivers. | pmid:25676507 |
Lucas CD et al. | Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25629436 |