MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Seong RK et al. | Wogonin, a flavonoid isolated from Scutellaria baicalensis, has anti-viral activities against influenza infection via modulation of AMPK pathways. | Acta Virol. | pmid:29521106 | |
pmid: | ||||
Kaneko T et al. | Inhibition of prostaglandin E2 production by flavone and its related compounds. | In Vivo | pmid:20133976 | |
Ono K et al. | Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. | 1990 | Eur. J. Biochem. | pmid:1695572 |
Huang HC et al. | Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell. | 1994 | Eur. J. Pharmacol. | pmid:8137874 |
Lin SJ et al. | Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography. | 1996 | J Chromatogr A | pmid:8680588 |
Tsai TH et al. | Determination of wogonin in rat plasma by liquid chromatography and its pharmacokinetic application. | 1996 | Planta Med. | pmid:8693042 |
Lin CC and Shieh DE | The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. | 1996 | Am. J. Chin. Med. | pmid:8739179 |
Park HJ et al. | Induction of quinone reductase by a methanol extract of Scutellaria baicalensis and its flavonoids in murine Hepa 1c1c7 cells. | 1998 | Eur. J. Cancer Prev. | pmid:9926295 |
Nakahata N et al. | Analysis of inhibitory effects of scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells. | 1998 | Am. J. Chin. Med. | pmid:9862019 |
Zhang YY et al. | Comparative study of Scutellaria planipes and Scutellaria baicalensis. | 1998 Jan-Feb | Biomed. Chromatogr. | pmid:9470972 |
Gao Z et al. | Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. | 1999 | Biochim. Biophys. Acta | pmid:10564778 |
Wakabayashi I | Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. | 1999 | Pharmacol. Toxicol. | pmid:10401731 |
Kim HM et al. | The nitric oxide-producing activities of Scutellaria baicalensis. | 1999 | Toxicology | pmid:10463767 |
Ueng YF et al. | Effects of baicalein and wogonin on drug-metabolizing enzymes in C57BL/6J mice. | 2000 | Life Sci. | pmid:11045600 |
Ikemoto S et al. | Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. | 2000 | Urology | pmid:10840124 |
Wakabayashi I and Yasui K | Wogonin inhibits inducible prostaglandin E(2) production in macrophages. | 2000 | Eur. J. Pharmacol. | pmid:11040356 |
Huang RL et al. | Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis. | 2000 | Planta Med. | pmid:11199123 |
Ueng YF et al. | Protective effects of baicalein and wogonin against benzo[a]pyrene- and aflatoxin B(1)-induced genotoxicities. | 2001 | Biochem. Pharmacol. | pmid:11755119 |
Zuo F et al. | Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography. | 2001 | Biol. Pharm. Bull. | pmid:11411561 |