Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Carcinoma D002277 18 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Penile Induration D010411 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Hong T et al. Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. 2002 Planta Med. pmid:11914968
Chang WH et al. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. 2002 Planta Med. pmid:11859462
Ma SC et al. Antiviral Chinese medicinal herbs against respiratory syncytial virus. 2002 J Ethnopharmacol pmid:11801383
Shen SC et al. In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. 2002 Eur. J. Pharmacol. pmid:12098601
Du Y et al. [Determination of wogonin in rat plasma by liquid chromatography-tandem mass spectrometry]. 2002 Yao Xue Xue Bao pmid:12579842
Chiu JH et al. Tumor necrosis factor-producing activity of wogonin in RAW 264.7 murine macrophage cell line. 2002 Planta Med. pmid:12451498
Nagaki Y et al. Effects of scutellariae radix extract and its components (baicalein, baicalin, and wogonin) on the experimental elevation of aqueous flare in pigmented rabbits. 2001 May-Jun Jpn. J. Ophthalmol. pmid:11369368
Kim H et al. The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. 2001 Neurosci. Lett. pmid:11489548
Chang YL et al. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. 2001 Mol. Pharmacol. pmid:11502881
Van Dien M et al. Protective effect of wogonin on endotoxin-induced lethal shock in D-galactosamine-sensitized mice. 2001 Microbiol. Immunol. pmid:11791668