MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma | D002277 | 18 associated lipids |
Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
Papillomavirus Infections | D030361 | 4 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma | D002277 | 18 associated lipids |
Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
Papillomavirus Infections | D030361 | 4 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Nam KW et al. | The role of wogonin in controlling SOCS3 expression in neuronal cells. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25035930 |
Hu Y et al. | Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17069758 |
Chen S et al. | Natural inhibitors of indoleamine 3,5-dioxygenase induced by interferon-gamma in human neural stem cells. | 2012 | Biochem. Biophys. Res. Commun. | pmid:23063682 |
Lim JS et al. | Wogonin induces differentiation and neurite outgrowth of neural precursor cells. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20888794 |
Li Y et al. | Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22560901 |
Hosseinzadeh Z et al. | Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25168590 |
Zhao L et al. | Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. | 2013 | Biochem. Cell Biol. | pmid:23859016 |
Yang L et al. | Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. | 2009 | Biochem. Cell Biol. | pmid:19935879 |
Lee DH et al. | Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. | 2008 | Biochem. Pharmacol. | pmid:18377871 |
Hui KM et al. | Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. | 2002 | Biochem. Pharmacol. | pmid:12392823 |