MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee W et al. | Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. | 2015 | Inflammation | pmid:25249339 |
Lucas CD et al. | Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25629436 |
Polier G et al. | Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. | 2015 | Int. J. Cancer | pmid:24895203 |
Zhao Y et al. | Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway. | 2015 | Mol. Carcinog. | pmid:24976450 |
Fong SY et al. | Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies. | 2014 | J Pharm Biomed Anal | pmid:24803030 |
Bak EJ et al. | Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice. | 2014 | Clin Nutr | pmid:23623334 |
Gong WY et al. | Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro. | 2014 | Int. J. Oncol. | pmid:24604573 |
Zhao K et al. | Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling. | 2014 | Eur. J. Pharmacol. | pmid:24858369 |
Qian C et al. | Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. | 2014 | Free Radic. Res. | pmid:24666416 |
Zhou M et al. | Wogonin inhibits H2O2-induced angiogenesis via suppressing PI3K/Akt/NF-κB signaling pathway. | 2014 | Vascul. Pharmacol. | pmid:24534483 |