MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kwak S et al. | Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. | 2014 | Toxicol. Appl. Pharmacol. | pmid:25223693 |
Shin HS et al. | Skullcap (Scutellaria baicalensis) extract and its active compound, wogonin, inhibit ovalbumin-induced Th2-mediated response. | 2014 | Molecules | pmid:24566319 |
Yeh CH et al. | Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells. | 2014 | Environ. Toxicol. | pmid:23362215 |
Marsh Z et al. | Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. | 2014 | Phytochemistry | pmid:25236693 |
Yang H et al. | Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells. | 2014 | Oncotarget | pmid:25149543 |
Yao J et al. | NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis. | 2014 | Cell Death Dis | pmid:24901054 |
Talbi A et al. | Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats. | 2014 | Molecules | pmid:24786691 |
Hosseinzadeh Z et al. | Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25168590 |
Ku SK and Bae JS | Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. | 2014 | Fitoterapia | pmid:25020199 |
Zhao K et al. | Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling. | 2014 | Eur. J. Pharmacol. | pmid:24858369 |