Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Breast Neoplasms D001943 24 associated lipids
Body Weight D001835 333 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Lin YT et al. Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. 2003 Biol. Pharm. Bull. pmid:12736527
Wang W et al. The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo. 2006 Biol. Pharm. Bull. pmid:16755005
Zuo F et al. Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. 2003 Biol. Pharm. Bull. pmid:12843610
Zuo F et al. Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora. 2002 Biol. Pharm. Bull. pmid:12033492
Liu ZL et al. Induction of apoptosis in human lung fibroblasts and peripheral lymphocytes in vitro by Shosaiko-to derived phenolic metabolites. 2002 Biol. Pharm. Bull. pmid:11824553
Zuo F et al. Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography. 2001 Biol. Pharm. Bull. pmid:11411561
Han CK et al. Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism. 2005 Biol. Pharm. Bull. pmid:16079475
Qu JT et al. Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study. 2015 Biol. Pharm. Bull. pmid:26632179
Kasai A et al. Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. 2008 Biol. Pharm. Bull. pmid:18451504
Cho J and Lee HK Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. 2004 Biol. Pharm. Bull. pmid:15467195