Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Glioma D005910 112 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Brain Ischemia D002545 89 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Xia Y et al. A novel process related impurity and forced degradation study of synthetic wogonin: development of a liquid chromatographic method for purity control. 2012 J Pharm Biomed Anal pmid:22906689
Shao YX et al. The molecular basis for the inhibition of human cytochrome P450 1A2 by oroxylin and wogonin. 2012 Eur. Biophys. J. pmid:22228220
Cao XD et al. Antitumor constituents from the leaves of Carya cathayensis. 2012 Nat. Prod. Res. pmid:22007794
Shi R et al. Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21514902
Ahn SH et al. Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. 2011 BMC Neurosci pmid:21810275
Gao J et al. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. 2011 Toxicol. Appl. Pharmacol. pmid:21457722
Park NI et al. Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. 2011 Funct. Integr. Genomics pmid:21538138
Zeng H et al. The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. 2011 J Ethnopharmacol pmid:21466840
Kimura Y and Sumiyoshi M Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. 2011 Eur. J. Pharmacol. pmid:21549115
Yang DZ et al. Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. 2011 Talanta pmid:21726714
Yu JS and Kim AK Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. 2011 Mol. Cells pmid:21448585
Zhao L et al. Developmental toxicity and genotoxicity studies of wogonin. 2011 Regul. Toxicol. Pharmacol. pmid:21459121
Chen P et al. Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. 2011 Toxicology pmid:21295103
Yang L et al. Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. 2011 Cancer Sci. pmid:21244577
Chow SE et al. Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. 2011 Cancer Chemother. Pharmacol. pmid:21207227
Chen CY et al. Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. 2011 J. Nutr. Biochem. pmid:21190831
Tayarani-Najaran Z et al. Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. 2011 Evid Based Complement Alternat Med pmid:20028719
Petraglia AL et al. Stuck at the bench: Potential natural neuroprotective compounds for concussion. 2011 Surg Neurol Int pmid:22059141
Samarghandian S et al. Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. 2011 Clinics (Sao Paulo) pmid:21808878
Lee MY et al. A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. 2011 Toxicol Int pmid:21976821