| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim EJ et al. | Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. | 2011 | Acta Physiol (Oxf) | pmid:21306568 |
| Shia CS et al. | Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. | 2011 | Evid Based Complement Alternat Med | pmid:19737807 |
| Chen CM et al. | Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. | 2011 | Evid Based Complement Alternat Med | pmid:19584080 |
| Liu YM et al. | Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway. | 2011 | Acta Pharmacol. Sin. | pmid:21986573 |
| Shi R et al. | Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21514902 |
| Gao J et al. | The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21457722 |
| Park NI et al. | Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. | 2011 | Funct. Integr. Genomics | pmid:21538138 |
| Gasiorowski K et al. | Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? | 2011 | CNS Neurol Disord Drug Targets | pmid:21222632 |
| Zeng H et al. | The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. | 2011 | J Ethnopharmacol | pmid:21466840 |
| Xie S et al. | Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. | 2011 | J. Pharm. Pharmacol. | pmid:21235595 |
| Kimura Y and Sumiyoshi M | Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. | 2011 | Eur. J. Pharmacol. | pmid:21549115 |
| Yang DZ et al. | Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. | 2011 | Talanta | pmid:21726714 |
| Li T et al. | Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. | 2011 | Eur J Drug Metab Pharmacokinet | pmid:21713461 |
| Lee YM et al. | Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21436723 |
| Chen FP et al. | Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. | 2011 | Evid Based Complement Alternat Med | pmid:19339485 |
| Tayarani-Najaran Z et al. | Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. | 2011 | Evid Based Complement Alternat Med | pmid:20028719 |
| Calvo TR et al. | Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. | 2011 | Evid Based Complement Alternat Med | pmid:19696193 |
| Wu B et al. | Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells. | 2011 | BMC Cancer | pmid:22204275 |
| Dong P et al. | Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin. | 2011 | J Ethnopharmacol | pmid:21855619 |
| Polier G et al. | Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. | 2011 | Cell Death Dis | pmid:21776020 |