Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Glioma D005910 112 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Brain Ischemia D002545 89 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Papillomavirus Infections D030361 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Hong T et al. Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. 2002 Planta Med. pmid:11914968
Chang WH et al. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. 2002 Planta Med. pmid:11859462
Ma SC et al. Antiviral Chinese medicinal herbs against respiratory syncytial virus. 2002 J Ethnopharmacol pmid:11801383
Lin YT et al. Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. 2003 Biol. Pharm. Bull. pmid:12736527
Lee HH et al. Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death. 2003 Brain Res. pmid:12965234
Lai MY et al. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. 2003 Biol. Pharm. Bull. pmid:12520178
Nakamura N et al. Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. 2003 Exp. Eye Res. pmid:12873450
Zuo F et al. Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. 2003 Biol. Pharm. Bull. pmid:12843610
Huang WH et al. Novel synthesis of flavonoids of Scutellaria baicalensis Georgi. 2003 Chem. Pharm. Bull. pmid:12612426
Lim BO Effects of wogonin, wogonoside, and 3,5,7,2',6'-pentahydroxyflavone on chemical mediator production in peritoneal exduate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes. 2003 J Ethnopharmacol pmid:12499072
Lee H et al. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. 2003 FASEB J. pmid:12897065
Li DR et al. [Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]. 2003 Ai Zheng pmid:12917023
Chi YS et al. Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression. 2003 Biochem. Pharmacol. pmid:14505806
Wang Z et al. Wogonin suppresses cellular proliferation and expression of monocyte chemoattractant protein 1 in Peyronie's plaque-derived cells. 2003 BJU Int. pmid:14616461
Pal M et al. Antifungal activity of wogonin. 2003 Phytother Res pmid:14669259
Lim BO et al. Effect of the flavonoid components obtained from Scutellaria radix on the histamine, immunoglobulin E and lipid peroxidation of spleen lymphocytes of Sprague-Dawley rats. 2003 Biosci. Biotechnol. Biochem. pmid:12834292
Nagaki Y et al. Effects of topical instillation of traditional herbal medicines, herbal extracts, and their components on prostaglandin E2-induced aqueous flare elevation in pigmented rabbits. 2003 May-Jun Jpn. J. Ophthalmol. pmid:12782159
Tian J et al. Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA. 2004 J. Photochem. Photobiol. B, Biol. pmid:15043845
Cho J and Lee HK Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. 2004 Biol. Pharm. Bull. pmid:15467195
Piao HZ et al. Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. 2004 Arch. Pharm. Res. pmid:15473663