| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang HW et al. | Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation. | 2008 | Eur. J. Pharmacol. | pmid:18577379 |
| Piao HZ et al. | Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. | 2008 | Int. Immunopharmacol. | pmid:18725324 |
| Lee CY et al. | Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. | 2008 | Liver Int. | pmid:18346132 |
| Chen S et al. | Down-regulation of androgen-receptor and PSA by phytochemicals. | 2008 | Int. J. Oncol. | pmid:18202763 |
| Kauss T et al. | Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis. | 2008 | Arthritis Res. Ther. | pmid:18252009 |
| Chung H et al. | Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts. | 2008 | Int. J. Cancer | pmid:17957784 |
| Baumann S et al. | Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. | 2008 | Blood | pmid:18070986 |
| Li YQ et al. | Two new alkaloids from Capparis himalayensis. | 2008 | Chem. Pharm. Bull. | pmid:18239306 |
| Zhang K et al. | Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. | 2008 | Cancer Sci. | pmid:18377421 |
| Lu N et al. | Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. | 2008 | Life Sci. | pmid:18378261 |
| Lin Z et al. | Enhanced electrochemiluminescence of Ru(bpy)3(2+) by flavone compounds. | 2008 Nov-Dec | Luminescence | pmid:18506909 |
| Yin L et al. | Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. | 2009 | J Pharm Biomed Anal | pmid:19264437 |
| Xu L et al. | Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. | 2009 | Anal. Chim. Acta | pmid:19110127 |
| Cao H et al. | Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. | 2009 | J. Hazard. Mater. | pmid:19577841 |
| Chen B et al. | Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. | 2009 | Int J Nanomedicine | pmid:20011242 |
| Willimott S et al. | An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. | 2009 | Chem Cent J | pmid:19785738 |
| Feng Y et al. | Bear bile: dilemma of traditional medicinal use and animal protection. | 2009 | J Ethnobiol Ethnomed | pmid:19138420 |
| Ding XF et al. | [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. | 2009 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:19650472 |
| Li C et al. | Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. | 2009 | J Pharm Biomed Anal | pmid:19481403 |
| Tran TD et al. | Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19233646 |
| Lee E et al. | Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723047 |
| Qi Q et al. | Toxicological studies of wogonin in experimental animals. | 2009 | Phytother Res | pmid:19003942 |
| Li-Weber M | New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. | 2009 | Cancer Treat. Rev. | pmid:19004559 |
| Rushworth SA and Micheau O | Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer. | 2009 | Br. J. Pharmacol. | pmid:19664138 |
| Peng J et al. | Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. | 2009 | J Ethnopharmacol | pmid:19397969 |
| Lee DH et al. | Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. | 2009 | Br. J. Pharmacol. | pmid:19438509 |
| Yang L et al. | Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. | 2009 | Biochem. Cell Biol. | pmid:19935879 |
| Wohlfarth C and Efferth T | Natural products as promising drug candidates for the treatment of hepatitis B and C. | 2009 | Acta Pharmacol. Sin. | pmid:19060918 |
| Kallifatidis G et al. | Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. | 2009 | Gut | pmid:18829980 |
| Li J et al. | Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. | 2009 | J. Nat. Prod. | pmid:19555121 |
| Gurung SK et al. | Inhibition of prostaglandin E2 production by synthetic wogonin analogs. | 2009 | Arch. Pharm. Res. | pmid:20091262 |
| Zhou XQ et al. | [Flavonoids from Scutellaria baicalensis and their bioactivities]. | 2009 | Beijing Da Xue Xue Bao | pmid:19829679 |
| Parekh HS et al. | A new dawn for the use of traditional Chinese medicine in cancer therapy. | 2009 | Mol. Cancer | pmid:19298677 |
| Parajuli P et al. | In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. | 2009 | Planta Med. | pmid:19031366 |
| Si D et al. | Mechanism of CYP2C9 inhibition by flavones and flavonols. | 2009 | Drug Metab. Dispos. | pmid:19074529 |
| Kim HS et al. | Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. | 2009 | J. Microbiol. Biotechnol. | pmid:20075633 |
| Kaneko T et al. | Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. | 2009 Jul-Aug | In Vivo | pmid:19567393 |
| Lu B et al. | Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. | 2009 Sep-Oct | Phytochem Anal | pmid:19533595 |
| Lin CW et al. | 12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. | 2010 | J. Cell. Physiol. | pmid:20458747 |
| Ni Y et al. | Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches. | 2010 | Anal. Chim. Acta | pmid:20206002 |
| Wang CZ et al. | Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. | 2010 | Phytomedicine | pmid:19836937 |
| Ye G et al. | Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. | 2010 | Chem. Biodivers. | pmid:21162005 |
| Li Y et al. | Combinative method using HPLC fingerprint and quantitative analyses for quality consistency evaluation of an herbal medicinal preparation produced by different manufacturers. | 2010 | J Pharm Biomed Anal | pmid:20138726 |
| Huang ST et al. | Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. | 2010 | Phytomedicine | pmid:19577445 |
| Cui X et al. | Traditional Chinese medicine and related active compounds against hepatitis B virus infection. | 2010 | Biosci Trends | pmid:20448340 |
| Zhao Q et al. | Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. | 2010 | Toxicol. Lett. | pmid:20570612 |
| Xu H et al. | Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. | 2010 | Bioresour. Technol. | pmid:20708926 |
| Schrader KK | Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). | 2010 | Toxins (Basel) | pmid:22069655 |
| Gao J et al. | Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. | 2010 | J Pharm Biomed Anal | pmid:20457505 |
| Feng J et al. | Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. | 2010 | J Pharm Biomed Anal | pmid:20430560 |