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Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. |
2014 |
Phytochemistry |
pmid:25236693
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Hong ZP et al. |
Wogonin exacerbates the cytotoxic effect of oxaliplatin by inducing nitrosative stress and autophagy in human gastric cancer cells. |
2018 |
Phytomedicine |
pmid:29433678
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Kimura Y and Sumiyoshi M |
Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis. |
2013 |
Phytomedicine |
pmid:23219337
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Wang CZ et al. |
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. |
2010 |
Phytomedicine |
pmid:19836937
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Huang ST et al. |
Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. |
2010 |
Phytomedicine |
pmid:19577445
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Ozmen A et al. |
In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey. |
2010 |
Phytomedicine |
pmid:19576743
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Sikder MA et al. |
Inhibition of TNF-α-induced MUC5AC mucin gene expression and production by wogonin through the inactivation of NF-κB signaling in airway epithelial cells. |
2014 |
Phytother Res |
pmid:23463646
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Jang S et al. |
Wogonin inhibits osteoclast formation induced by lipopolysaccharide. |
2010 |
Phytother Res |
pmid:19998398
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Pal M et al. |
Antifungal activity of wogonin. |
2003 |
Phytother Res |
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Toxicological studies of wogonin in experimental animals. |
2009 |
Phytother Res |
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Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents. |
2007 |
Phytother Res |
pmid:17674423
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Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin. |
2012 |
Phytother Res |
pmid:22388989
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Heo HJ et al. |
Effects of baicalin and wogonin on mucin release from cultured airway epithelial cells. |
2007 |
Phytother Res |
pmid:17622975
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Chaudhuri PK et al. |
Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea. |
2004 |
Phytother Res |
pmid:15022161
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Murch SJ et al. |
A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds. |
2004 |
Plant Cell Rep. |
pmid:15449017
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Chuang HN et al. |
Enhancing effects of Scutellaria baicalensis and some of its constituents on TGF-beta1 gene expression in RAW 264.7 murine macrophage cell line. |
2005 |
Planta Med. |
pmid:15931583
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Hong T et al. |
Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. |
2002 |
Planta Med. |
pmid:11914968
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Chang WH et al. |
Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. |
2002 |
Planta Med. |
pmid:11859462
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Lin CM et al. |
Wogonin inhibits IL-6-induced angiogenesis via down-regulation of VEGF and VEGFR-1, not VEGFR-2. |
2006 |
Planta Med. |
pmid:17024605
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Park EJ et al. |
Skullcapflavone I from Scutellaria baicalensis induces apoptosis in activated rat hepatic stellate cells. |
2005 |
Planta Med. |
pmid:16206047
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Lim H and Kim HP |
Inhibition of mammalian collagenase, matrix metalloproteinase-1, by naturally-occurring flavonoids. |
2007 |
Planta Med. |
pmid:17886198
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Determination of wogonin in rat plasma by liquid chromatography and its pharmacokinetic application. |
1996 |
Planta Med. |
pmid:8693042
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Chiu JH et al. |
Tumor necrosis factor-producing activity of wogonin in RAW 264.7 murine macrophage cell line. |
2002 |
Planta Med. |
pmid:12451498
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Cole IB et al. |
Comparisons of Scutellaria baicalensis, Scutellaria lateriflora and Scutellaria racemosa: genome size, antioxidant potential and phytochemistry. |
2008 |
Planta Med. |
pmid:18484546
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Parajuli P et al. |
In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. |
2009 |
Planta Med. |
pmid:19031366
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Kim BR et al. |
Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. |
2001 |
Planta Med. |
pmid:11488450
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Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity. |
2013 |
Planta Med. |
pmid:23818268
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Huang RL et al. |
Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis. |
2000 |
Planta Med. |
pmid:11199123
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Hou YC et al. |
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. |
2011 |
Planta Med. |
pmid:20957598
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Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury. |
2012 |
PLoS ONE |
pmid:22272328
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Yang Y et al. |
Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. |
2012 |
PLoS ONE |
pmid:23251389
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Chen XM et al. |
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. |
2013 |
PLoS ONE |
pmid:24265759
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Ci X et al. |
Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury. |
2012 |
PLoS ONE |
pmid:22563373
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Liu J et al. |
Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression. |
2015 |
PLoS ONE |
pmid:26317778
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Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. |
2011 |
PLoS ONE |
pmid:21779360
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Kudo M et al. |
Bifunctional effects of O-methylated flavones from Scutellaria baicalensis Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport. |
2017 |
PLoS ONE |
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Zhao K et al. |
Wogonin suppresses melanoma cell B16-F10 invasion and migration by inhibiting Ras-medicated pathways. |
2014 |
PLoS ONE |
pmid:25203554
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Zhu J et al. |
Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis. |
2012 |
PLoS ONE |
pmid:22590504
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Kang SH et al. |
Icariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signaling. |
2012 |
PLoS ONE |
pmid:22493659
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Chi YS and Kim HP |
Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix. |
2005 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:15589400
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Ong ES et al. |
Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. |
2004 |
Rapid Commun. Mass Spectrom. |
pmid:15468106
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Zhao L et al. |
Developmental toxicity and genotoxicity studies of wogonin. |
2011 |
Regul. Toxicol. Pharmacol. |
pmid:21459121
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Zhao Q et al. |
A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis. |
2016 |
Sci Adv |
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Katrahalli U et al. |
Interaction of bioactive coomassie brilliant blue g with protein: insights from spectroscopic methods. |
2010 Oct-Dec |
Sci Pharm |
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Xu X et al. |
Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation. |
2017 |
Sci Rep |
pmid:28150717
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Khan NM et al. |
A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes. |
2017 |
Sci Rep |
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Ma X et al. |
[Wogonin inhibits IGF-1-stimulated cell growth and estrogen receptor α expression in breast adenocarcinoma cell and angiogenesis of chick chorioallantoic membrane]. |
2012 |
Sheng Li Xue Bao |
pmid:22513472
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[Recombinant soluble CD40 ligand enhances Wogonin-induced antitumor activity]. |
2013 |
Sichuan Da Xue Xue Bao Yi Xue Ban |
pmid:24490490
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Li J et al. |
Studying on inclusion complexes of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin. |
2012 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:22192416
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Petraglia AL et al. |
Stuck at the bench: Potential natural neuroprotective compounds for concussion. |
2011 |
Surg Neurol Int |
pmid:22059141
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Yang DZ et al. |
Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. |
2011 |
Talanta |
pmid:21726714
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Yeh CH et al. |
Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cells. |
2015 |
Toxicol Ind Health |
pmid:23592745
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Lee MY et al. |
A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. |
2011 |
Toxicol Int |
pmid:21976821
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Kwak S et al. |
Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:25223693
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Song X et al. |
Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein. |
2013 |
Toxicol. Appl. Pharmacol. |
pmid:23707765
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Gao J et al. |
The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. |
2011 |
Toxicol. Appl. Pharmacol. |
pmid:21457722
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Wang Y et al. |
GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. |
2013 |
Toxicol. Lett. |
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Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. |
2004 |
Toxicol. Lett. |
pmid:14700523
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Zhao Q et al. |
Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. |
2010 |
Toxicol. Lett. |
pmid:20570612
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Wang F et al. |
Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. |
2013 |
Toxicology |
pmid:23246481
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He L et al. |
Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. |
2013 |
Toxicology |
pmid:23907061
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Chirumbolo S |
Anticancer properties of the flavone wogonin. |
2013 |
Toxicology |
pmid:23994129
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Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. |
2011 |
Toxicology |
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The nitric oxide-producing activities of Scutellaria baicalensis. |
1999 |
Toxicology |
pmid:10463767
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Schrader KK |
Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). |
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Toxins (Basel) |
pmid:22069655
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Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. |
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Urology |
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Wogonin inhibits LPS-induced vascular permeability via suppressing MLCK/MLC pathway. |
2015 |
Vascul. Pharmacol. |
pmid:25956732
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Wogonin inhibits H2O2-induced angiogenesis via suppressing PI3K/Akt/NF-κB signaling pathway. |
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Vascul. Pharmacol. |
pmid:24534483
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Fong SY and Zuo Z |
Species difference in the inhibitory potentials of non-steroidal anti-inflammatory drugs on the hepatic sulfation and glucuronidation of bioactive flavonoids: differential observations among common inhibition parameters. |
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Xenobiotica |
pmid:24168065
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[Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba]. |
2002 |
Yakugaku Zasshi |
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2006 |
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[Determination of wogonin in rat plasma by liquid chromatography-tandem mass spectrometry]. |
2002 |
Yao Xue Xue Bao |
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Molecular targets of dietary polyphenols with anti-inflammatory properties. |
2005 |
Yonsei Med. J. |
pmid:16259055
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2014 |
Zhongguo Zhong Yao Za Zhi |
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[Studies on chemical constituents in bark of dictamnus dasycarpus]. |
2005 |
Zhongguo Zhong Yao Za Zhi |
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