Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Hung CW et al. Stem cell-based neuroprotective and neurorestorative strategies. 2010 Int J Mol Sci pmid:20559500
Jang S et al. Wogonin inhibits osteoclast formation induced by lipopolysaccharide. 2010 Phytother Res pmid:19998398
Meng X et al. Effects of Various Flavonoids on the α-Synuclein Fibrillation Process. 2010 Parkinsons Dis pmid:20976092
Zhou Q et al. Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes. 2010 Pharm. Res. pmid:20411407
Khoo BY et al. Apoptotic effects of chrysin in human cancer cell lines. 2010 Int J Mol Sci pmid:20559509
Wang CZ et al. Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. 2010 Phytomedicine pmid:19836937
Ye G et al. Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. 2010 Chem. Biodivers. pmid:21162005
Tilton R et al. A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906. 2010 Chin Med pmid:20727161
Liang X et al. Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. 2010 J Pharm Biomed Anal pmid:19783115
Wei L et al. Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. 2010 J. Cell. Biochem. pmid:21053277
Lim JS et al. Wogonin induces differentiation and neurite outgrowth of neural precursor cells. 2010 Biochem. Biophys. Res. Commun. pmid:20888794
Lei W et al. Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. 2010 Genet. Mol. Biol. pmid:21637484
Huang ST et al. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. 2010 Phytomedicine pmid:19577445
Ijaz AZ et al. MKEM: a Multi-level Knowledge Emergence Model for mining undiscovered public knowledge. 2010 BMC Bioinformatics pmid:20406501
Ozmen A et al. In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey. 2010 Phytomedicine pmid:19576743
Ishii K et al. Effects of naturally occurring polymethyoxyflavonoids on cell growth, p-glycoprotein function, cell cycle, and apoptosis of daunorubicin-resistant T lymphoblastoid leukemia cells. 2010 Cancer Invest. pmid:19863351
Kong EK et al. Baicalein and Wogonin inhibit collagen deposition in SHR and WKY cardiac fibroblast cultures. 2010 BMB Rep pmid:20423617
Katrahalli U et al. Interaction of bioactive coomassie brilliant blue g with protein: insights from spectroscopic methods. 2010 Oct-Dec Sci Pharm pmid:21179322
Tan W et al. Anti-cancer natural products isolated from chinese medicinal herbs. 2011 Chin Med pmid:21777476
Hou YC et al. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. 2011 Planta Med. pmid:20957598