MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lucas CD et al. | Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25629436 |
Persson C | Drug-induced death of eosinophils. Promises and pitfalls. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25767918 |
Chen H et al. | A new strategy for quality control and qualitative analysis of Yinhuang preparations by HPLC-DAD-MS/MS. | 2012 | Anal Bioanal Chem | pmid:22885972 |
Xu L et al. | Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. | 2009 | Anal. Chim. Acta | pmid:19110127 |
Ni Y et al. | Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches. | 2010 | Anal. Chim. Acta | pmid:20206002 |
Lee E et al. | Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723047 |
Enomoto R et al. | Wogonin prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17404053 |
Lee E et al. | Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17404065 |
Wang W et al. | Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. | 2006 | Anticancer Drugs | pmid:16926629 |
Yu CS et al. | Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. | 2005 Jan-Feb | Anticancer Res. | pmid:15816529 |
Guo Q et al. | Anti-hepatitis B virus activity of wogonin in vitro and in vivo. | 2007 | Antiviral Res. | pmid:17280723 |
Yang L et al. | Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins. | 2013 | Apoptosis | pmid:23371323 |
Kim EH et al. | Targeting Nrf2 with wogonin overcomes cisplatin resistance in head and neck cancer. | 2016 | Apoptosis | pmid:27544755 |
Ku SK et al. | Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. | 2015 | Arch. Pharm. Res. | pmid:25564337 |
Dao TT et al. | Synthesis and biological activities of 8-arylflavones. | 2004 | Arch. Pharm. Res. | pmid:15089030 |
Dao TT et al. | Synthesis and iNOS inhibitory activities of thioflavones. | 2005 | Arch. Pharm. Res. | pmid:16042072 |
Jang J et al. | Structure and antiinflammatory activity relationships of wogonin derivatives. | 2005 | Arch. Pharm. Res. | pmid:16178410 |
Lim H et al. | Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. | 2004 | Arch. Pharm. Res. | pmid:15180311 |
Gurung SK et al. | Inhibition of prostaglandin E2 production by synthetic wogonin analogs. | 2009 | Arch. Pharm. Res. | pmid:20091262 |
Piao HZ et al. | Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. | 2004 | Arch. Pharm. Res. | pmid:15473663 |