MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma | D002277 | 18 associated lipids |
Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
Papillomavirus Infections | D030361 | 4 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma | D002277 | 18 associated lipids |
Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
Papillomavirus Infections | D030361 | 4 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Hong ZP et al. | Wogonin exacerbates the cytotoxic effect of oxaliplatin by inducing nitrosative stress and autophagy in human gastric cancer cells. | 2018 | Phytomedicine | pmid:29433678 |
Zhang Y et al. | The Influence of Compatibility of Rhubarb and Radix Scutellariae on the Pharmacokinetics of Anthraquinones and Flavonoids in Rat Plasma. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29134502 |
Fong SYK et al. | Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice. | 2017 | Mol. Pharm. | pmid:28426226 |
Wang J et al. | Mediating macrophage immunity with wogonin in mice with vascular inflammation. | 2017 | Mol Med Rep | pmid:28983597 |
Kapoor S | Protective effects of wogonin against disease progression in different hepatic pathological conditions. | 2017 | Int. Immunopharmacol. | pmid:28886583 |
Li HD et al. | Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease. | 2017 | Int. Immunopharmacol. | pmid:28646664 |
Xu X et al. | Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation. | 2017 | Sci Rep | pmid:28150717 |
Wang J et al. | Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro. | 2017 | Eur J Med Chem | pmid:28987604 |
Salmani JMM et al. | Development of a new HPLC method for wogonin in rat plasma: Compatibility of standard and test samples. | 2017 | Acta Pharm | pmid:28858841 |
Al-Maghout T et al. | P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na+/Ca2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes. | 2017 | Cell. Physiol. Biochem. | pmid:28813704 |