| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yu C et al. | Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis. | 2013 | Pharm Biol | pmid:23738852 |
| Song X et al. | Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23707765 |
| Zhang M et al. | Wogonin induces apoptosis in RPMI 8226, a human myeloma cell line, by downregulating phospho-Akt and overexpressing Bax. | 2013 | Life Sci. | pmid:23142241 |
| Chengcheng G et al. | Probe substrate and enzyme source-dependent inhibition of UDP-glucuronosyltransferase (UGT) 1A9 by wogonin. | 2013 | Afr Health Sci | pmid:24250287 |
| Chen XM et al. | Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. | 2013 | PLoS ONE | pmid:24265759 |
| He L et al. | Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. | 2013 | Toxicology | pmid:23907061 |
| Chirumbolo S | Anticancer properties of the flavone wogonin. | 2013 | Toxicology | pmid:23994129 |
| Chen CC et al. | Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury. | 2012 | PLoS ONE | pmid:22272328 |
| Xia Y et al. | A novel process related impurity and forced degradation study of synthetic wogonin: development of a liquid chromatographic method for purity control. | 2012 | J Pharm Biomed Anal | pmid:22906689 |
| Shao YX et al. | The molecular basis for the inhibition of human cytochrome P450 1A2 by oroxylin and wogonin. | 2012 | Eur. Biophys. J. | pmid:22228220 |
| Li J et al. | Studying on inclusion complexes of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22192416 |
| Zhu Y et al. | Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:22883103 |
| Chow SE et al. | Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. | 2012 | J. Cell. Biochem. | pmid:22689083 |
| Tong L et al. | Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry. | 2012 | J Pharm Biomed Anal | pmid:22703838 |
| Chen H et al. | A new strategy for quality control and qualitative analysis of Yinhuang preparations by HPLC-DAD-MS/MS. | 2012 | Anal Bioanal Chem | pmid:22885972 |
| Hayasaka S et al. | Traditional Japanese herbal (kampo) medicines and treatment of ocular diseases: a review. | 2012 | Am. J. Chin. Med. | pmid:22928823 |
| Wilczańska-Barska A et al. | Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. | 2012 | Biotechnol. Lett. | pmid:22639092 |
| Lu QY et al. | Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. | 2012 | Pancreas | pmid:22158070 |
| Li C et al. | Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. | 2012 | AAPS J | pmid:22167378 |
| Ding J et al. | Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression. | 2012 | J. Biol. Chem. | pmid:22086925 |