Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Acute Lung Injury D055371 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
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Authors Title Published Journal PubMed Link
Lin Z et al. Enhanced electrochemiluminescence of Ru(bpy)3(2+) by flavone compounds. 2008 Nov-Dec Luminescence pmid:18506909
Yin L et al. Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. 2009 J Pharm Biomed Anal pmid:19264437
Xu L et al. Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. 2009 Anal. Chim. Acta pmid:19110127
Cao H et al. Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. 2009 J. Hazard. Mater. pmid:19577841
Chen B et al. Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. 2009 Int J Nanomedicine pmid:20011242
Willimott S et al. An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. 2009 Chem Cent J pmid:19785738
Feng Y et al. Bear bile: dilemma of traditional medicinal use and animal protection. 2009 J Ethnobiol Ethnomed pmid:19138420
Li C et al. Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. 2009 J Pharm Biomed Anal pmid:19481403
Tran TD et al. Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. 2009 Bioorg. Med. Chem. Lett. pmid:19233646
Lee E et al. Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. 2009 Ann. N. Y. Acad. Sci. pmid:19723047
Li-Weber M New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. 2009 Cancer Treat. Rev. pmid:19004559
Wohlfarth C and Efferth T Natural products as promising drug candidates for the treatment of hepatitis B and C. 2009 Acta Pharmacol. Sin. pmid:19060918
Kallifatidis G et al. Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. 2009 Gut pmid:18829980
Li J et al. Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. 2009 J. Nat. Prod. pmid:19555121
Gurung SK et al. Inhibition of prostaglandin E2 production by synthetic wogonin analogs. 2009 Arch. Pharm. Res. pmid:20091262
Zhou XQ et al. [Flavonoids from Scutellaria baicalensis and their bioactivities]. 2009 Beijing Da Xue Xue Bao pmid:19829679
Parekh HS et al. A new dawn for the use of traditional Chinese medicine in cancer therapy. 2009 Mol. Cancer pmid:19298677
Parajuli P et al. In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. 2009 Planta Med. pmid:19031366
Si D et al. Mechanism of CYP2C9 inhibition by flavones and flavonols. 2009 Drug Metab. Dispos. pmid:19074529
Kim HS et al. Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. 2009 J. Microbiol. Biotechnol. pmid:20075633