MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Breast Neoplasms | D001943 | 24 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen CC et al. | Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury. | 2012 | PLoS ONE | pmid:22272328 |
Dong LL et al. | An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix. | 2012 | Food Chem | pmid:25683416 |
Chen SS et al. | Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. | 2012 | Discov Med | pmid:22284780 |
Li X et al. | Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. | 2012 | Evid Based Complement Alternat Med | pmid:22235229 |
Chow SE et al. | Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. | 2012 | J. Cell. Biochem. | pmid:22689083 |
Pham TA et al. | Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22366656 |
Ha SK et al. | 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. | 2012 | Neuropharmacology | pmid:22465818 |
Chen S et al. | Natural inhibitors of indoleamine 3,5-dioxygenase induced by interferon-gamma in human neural stem cells. | 2012 | Biochem. Biophys. Res. Commun. | pmid:23063682 |
Li Y et al. | Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22560901 |
Li WJ et al. | Phenolic compounds and antioxidant activities of Liriope muscari. | 2012 | Molecules | pmid:22328078 |
Matsunaga T et al. | Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. | 2012 | Front Pharmacol | pmid:22319498 |
Ho FM et al. | Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. | 2012 | J Ethnopharmacol | pmid:22543166 |
Wilczańska-Barska A et al. | Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. | 2012 | Biotechnol. Lett. | pmid:22639092 |
He H et al. | Screening active compounds acting on the epidermal growth factor receptor from Radix scutellariae via cell membrane chromatography online coupled with HPLC/MS. | 2012 | J Pharm Biomed Anal | pmid:22260968 |
Islam MN et al. | A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract. | 2012 | Nat. Prod. Res. | pmid:22304335 |
Lu QY et al. | Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. | 2012 | Pancreas | pmid:22158070 |
Li C et al. | Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. | 2012 | AAPS J | pmid:22167378 |
Chi DS et al. | Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. | 2012 | Clin Mol Allergy | pmid:22309647 |
Kim JO et al. | Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin. | 2012 | Phytother Res | pmid:22388989 |
Zhang N et al. | A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. | 2012 | Evid Based Complement Alternat Med | pmid:22272213 |