Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Breast Neoplasms D001943 24 associated lipids
Body Weight D001835 333 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Li-Weber M New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. 2009 Cancer Treat. Rev. pmid:19004559
Qi Q et al. Toxicological studies of wogonin in experimental animals. 2009 Phytother Res pmid:19003942
Kallifatidis G et al. Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. 2009 Gut pmid:18829980
BÅ‚ach-Olszewska Z et al. Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. 2008 J. Interferon Cytokine Res. pmid:18771341
Piao HZ et al. Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. 2008 Int. Immunopharmacol. pmid:18725324
Dai JY et al. Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu- tang across human intestinal Caco-2 cell monolayers. 2008 Acta Pharmacol. Sin. pmid:18718184
Su S et al. Genetic characterization and phytochemical analysis of wild and cultivated populations of Scutellaria baicalensis. 2008 Chem. Biodivers. pmid:18651621
Anand P et al. Cancer is a preventable disease that requires major lifestyle changes. 2008 Pharm. Res. pmid:18626751
Zhang HW et al. Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation. 2008 Eur. J. Pharmacol. pmid:18577379
Lin Z et al. Enhanced electrochemiluminescence of Ru(bpy)3(2+) by flavone compounds. 2008 Nov-Dec Luminescence pmid:18506909
Chen LG et al. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. 2008 Mol Nutr Food Res pmid:18496814
Cole IB et al. Comparisons of Scutellaria baicalensis, Scutellaria lateriflora and Scutellaria racemosa: genome size, antioxidant potential and phytochemistry. 2008 Planta Med. pmid:18484546
Kasai A et al. Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. 2008 Biol. Pharm. Bull. pmid:18451504
Gao J et al. Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. 2008 J Pharm Pharm Sci pmid:18445366
Ohta Y et al. Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue. 2007 J Clin Biochem Nutr pmid:18437211
Makino T et al. Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products. 2008 J Nat Med pmid:18404307
Lu N et al. Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. 2008 Life Sci. pmid:18378261
Lee DH et al. Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. 2008 Biochem. Pharmacol. pmid:18377871
Zhang K et al. Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. 2008 Cancer Sci. pmid:18377421
Lee CY et al. Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. 2008 Liver Int. pmid:18346132