MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Park H et al. | Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives. | 2005 | Eur J Med Chem | pmid:15963606 |
Dao TT et al. | Synthesis and biological activities of 8-arylflavones. | 2004 | Arch. Pharm. Res. | pmid:15089030 |
Sonoda M et al. | Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. | 2004 | J Ethnopharmacol | pmid:15036470 |
Woźniak D et al. | Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. | 2004 | Nahrung | pmid:15053344 |
Murch SJ et al. | A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds. | 2004 | Plant Cell Rep. | pmid:15449017 |
Scuro LS et al. | Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation. | 2004 | BMC Biochem. | pmid:15102332 |
Son D et al. | Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. | 2004 | Eur. J. Pharmacol. | pmid:15189769 |
Lim H et al. | Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. | 2004 | Arch. Pharm. Res. | pmid:15180311 |
Park S et al. | Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats. | 2004 | Dig. Dis. Sci. | pmid:15139485 |
Cho J and Lee HK | Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. | 2004 | Eur. J. Pharmacol. | pmid:14757129 |
Li HB et al. | Separation methods used for Scutellaria baicalensis active components. | 2004 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15556504 |
Ong ES et al. | Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15468106 |
Chen TJ et al. | Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. | 2004 | Toxicol. Lett. | pmid:14700523 |
Lim BO | Efficacy of wogonin in the production of immunoglobulins and cytokines by mesenteric lymph node lymphocytes in mouse colitis induced with dextran sulfate sodium. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618621 |
Chaudhuri PK et al. | Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea. | 2004 | Phytother Res | pmid:15022161 |
Tian J et al. | Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA. | 2004 | J. Photochem. Photobiol. B, Biol. | pmid:15043845 |
Cho J and Lee HK | Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. | 2004 | Biol. Pharm. Bull. | pmid:15467195 |
Piao HZ et al. | Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. | 2004 | Arch. Pharm. Res. | pmid:15473663 |
Nagaki Y et al. | Effects of topical instillation of traditional herbal medicines, herbal extracts, and their components on prostaglandin E2-induced aqueous flare elevation in pigmented rabbits. | 2003 May-Jun | Jpn. J. Ophthalmol. | pmid:12782159 |
Zuo F et al. | Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. | 2003 | Biol. Pharm. Bull. | pmid:12843610 |