MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Scuro LS et al. | Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation. | 2004 | BMC Biochem. | pmid:15102332 |
Dao TT et al. | Synthesis and biological activities of 8-arylflavones. | 2004 | Arch. Pharm. Res. | pmid:15089030 |
Woźniak D et al. | Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. | 2004 | Nahrung | pmid:15053344 |
Tian J et al. | Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA. | 2004 | J. Photochem. Photobiol. B, Biol. | pmid:15043845 |
Sonoda M et al. | Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. | 2004 | J Ethnopharmacol | pmid:15036470 |
Chaudhuri PK et al. | Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea. | 2004 | Phytother Res | pmid:15022161 |
Cho J and Lee HK | Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. | 2004 | Eur. J. Pharmacol. | pmid:14757129 |
Chen TJ et al. | Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. | 2004 | Toxicol. Lett. | pmid:14700523 |
Pal M et al. | Antifungal activity of wogonin. | 2003 | Phytother Res | pmid:14669259 |
Wang Z et al. | Wogonin suppresses cellular proliferation and expression of monocyte chemoattractant protein 1 in Peyronie's plaque-derived cells. | 2003 | BJU Int. | pmid:14616461 |
Chi YS et al. | Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression. | 2003 | Biochem. Pharmacol. | pmid:14505806 |
Lee HH et al. | Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death. | 2003 | Brain Res. | pmid:12965234 |
Li DR et al. | [Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]. | 2003 | Ai Zheng | pmid:12917023 |
Lee H et al. | Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. | 2003 | FASEB J. | pmid:12897065 |
Nakamura N et al. | Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. | 2003 | Exp. Eye Res. | pmid:12873450 |
Zuo F et al. | Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats. | 2003 | Biol. Pharm. Bull. | pmid:12843610 |
Lim BO et al. | Effect of the flavonoid components obtained from Scutellaria radix on the histamine, immunoglobulin E and lipid peroxidation of spleen lymphocytes of Sprague-Dawley rats. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12834292 |
Nagaki Y et al. | Effects of topical instillation of traditional herbal medicines, herbal extracts, and their components on prostaglandin E2-induced aqueous flare elevation in pigmented rabbits. | 2003 May-Jun | Jpn. J. Ophthalmol. | pmid:12782159 |
Lin YT et al. | Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. | 2003 | Biol. Pharm. Bull. | pmid:12736527 |
Huang WH et al. | Novel synthesis of flavonoids of Scutellaria baicalensis Georgi. | 2003 | Chem. Pharm. Bull. | pmid:12612426 |