MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lei W et al. | Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. | 2010 | Genet. Mol. Biol. | pmid:21637484 |
Ding XF et al. | [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. | 2009 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:19650472 |
Kallifatidis G et al. | Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. | 2009 | Gut | pmid:18829980 |
Yu JQ et al. | Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. | 2007 | Hepatol. Res. | pmid:17300700 |
Yao J et al. | Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway. | 2014 | Immunology | pmid:24766487 |
Lin CC et al. | Wogonin, a natural and biologically-active flavonoid, influences a murine WEHI-3 leukemia model in vivo through enhancing populations of T- and B-cells. | 2013 Nov-Dec | In Vivo | pmid:24292576 |
Kaneko T et al. | Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. | 2009 Jul-Aug | In Vivo | pmid:19567393 |
Tang NY et al. | Effects of wogonin on the levels of cytokines and functions of leukocytes associated with NF-kappa B expression in Sprague-Dawley rats. | 2006 Jul-Aug | In Vivo | pmid:16900784 |
Kaneko T et al. | Inhibition of prostaglandin E2 production by flavone and its related compounds. | In Vivo | pmid:20133976 | |
Wang W et al. | Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. | 2015 | Inflamm. Res. | pmid:25917044 |
Lee W et al. | Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. | 2015 | Inflammation | pmid:25249339 |
Hung CW et al. | Stem cell-based neuroprotective and neurorestorative strategies. | 2010 | Int J Mol Sci | pmid:20559500 |
Khoo BY et al. | Apoptotic effects of chrysin in human cancer cell lines. | 2010 | Int J Mol Sci | pmid:20559509 |
Mazzio EA et al. | The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | 2011 | Int J Mol Sci | pmid:21340000 |
Tsai CF et al. | Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells. | 2012 | Int J Mol Sci | pmid:22949836 |
Zhang H et al. | A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway. | 2016 | Int J Mol Sci | pmid:27196894 |
Chen B et al. | Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. | 2009 | Int J Nanomedicine | pmid:20011242 |
Cheng J et al. | Effect of magnetic nanoparticles of Fe3O4 and wogonin on the reversal of multidrug resistance in K562/A02 cell line. | 2012 | Int J Nanomedicine | pmid:22745547 |
Wang L et al. | Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells. | 2012 | Int J Nanomedicine | pmid:22359456 |
Yu H et al. | Enhancement of solubility and dissolution rate of baicalein, wogonin and oroxylin A extracted from Radix scutellariae. | 2017 | Int J Pharm | pmid:28642200 |