Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Penile Induration D010411 4 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Kim EJ et al. Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. 2011 Acta Physiol (Oxf) pmid:21306568
Chen CM et al. Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. 2011 Evid Based Complement Alternat Med pmid:19584080
Shih YT et al. San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. 2011 Evid Based Complement Alternat Med pmid:19339484
Li C et al. Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. 2011 J Pharm Biomed Anal pmid:21051171
Ahn SH et al. Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. 2011 BMC Neurosci pmid:21810275
Tan W et al. Anti-cancer natural products isolated from chinese medicinal herbs. 2011 Chin Med pmid:21777476
Gasiorowski K et al. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? 2011 CNS Neurol Disord Drug Targets pmid:21222632
Xie S et al. Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. 2011 J. Pharm. Pharmacol. pmid:21235595
Chen J et al. Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. 2011 Biomed. Chromatogr. pmid:21154891
Lee YM et al. Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats. 2011 J. Cardiovasc. Pharmacol. pmid:21436723
Yu JS and Kim AK Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. 2011 Mol. Cells pmid:21448585
Zhao L et al. Developmental toxicity and genotoxicity studies of wogonin. 2011 Regul. Toxicol. Pharmacol. pmid:21459121
Chen P et al. Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. 2011 Toxicology pmid:21295103
Yang L et al. Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. 2011 Cancer Sci. pmid:21244577
Messaoudene D et al. Ex vivo effects of flavonoïds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behçet's disease. 2011 J Inflamm (Lond) pmid:22104639
Chen FP et al. Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. 2011 Evid Based Complement Alternat Med pmid:19339485
Calvo TR et al. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. 2011 Evid Based Complement Alternat Med pmid:19696193
Petraglia AL et al. Stuck at the bench: Potential natural neuroprotective compounds for concussion. 2011 Surg Neurol Int pmid:22059141
Samarghandian S et al. Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. 2011 Clinics (Sao Paulo) pmid:21808878
Lee MY et al. A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. 2011 Toxicol Int pmid:21976821