Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Penile Induration D010411 4 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Authors Title Published Journal PubMed Link
Chen CC et al. Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury. 2012 PLoS ONE pmid:22272328
Xia Y et al. A novel process related impurity and forced degradation study of synthetic wogonin: development of a liquid chromatographic method for purity control. 2012 J Pharm Biomed Anal pmid:22906689
Zhu Y et al. Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22883103
Chen SS et al. Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. 2012 Discov Med pmid:22284780
Li X et al. Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. 2012 Evid Based Complement Alternat Med pmid:22235229
Chow SE et al. Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. 2012 J. Cell. Biochem. pmid:22689083
Tong L et al. Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry. 2012 J Pharm Biomed Anal pmid:22703838
Chen H et al. A new strategy for quality control and qualitative analysis of Yinhuang preparations by HPLC-DAD-MS/MS. 2012 Anal Bioanal Chem pmid:22885972
Ha SK et al. 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. 2012 Neuropharmacology pmid:22465818
Hayasaka S et al. Traditional Japanese herbal (kampo) medicines and treatment of ocular diseases: a review. 2012 Am. J. Chin. Med. pmid:22928823
Li Y et al. Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. 2012 Biochem. Biophys. Res. Commun. pmid:22560901
Li WJ et al. Phenolic compounds and antioxidant activities of Liriope muscari. 2012 Molecules pmid:22328078
Matsunaga T et al. Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. 2012 Front Pharmacol pmid:22319498
Ho FM et al. Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. 2012 J Ethnopharmacol pmid:22543166
Wilczańska-Barska A et al. Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. 2012 Biotechnol. Lett. pmid:22639092
Eylenstein A et al. Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions. 2012 J. Biol. Chem. pmid:22110130
Lu QY et al. Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. 2012 Pancreas pmid:22158070
Li C et al. Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. 2012 AAPS J pmid:22167378
Chi DS et al. Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. 2012 Clin Mol Allergy pmid:22309647
Zhang N et al. A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. 2012 Evid Based Complement Alternat Med pmid:22272213