| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xu F et al. | The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters. | 2013 | J Pharm Sci | pmid:24018852 |
| Oshima N et al. | Quantitative analysis of anti-inflammatory activity of orengedokuto: importance of combination of flavonoids in inhibition of PGE2 production in mouse macrophage-like cell line J774.1. | 2013 | J Nat Med | pmid:22729955 |
| Yu C et al. | Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis. | 2013 | Pharm Biol | pmid:23738852 |
| Wang Y et al. | GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. | 2013 | Toxicol. Lett. | pmid:23872260 |
| Zhao L et al. | Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. | 2013 | Biochem. Cell Biol. | pmid:23859016 |
| Wang F et al. | Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. | 2013 | Toxicology | pmid:23246481 |
| Kimura Y and Sumiyoshi M | Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis. | 2013 | Phytomedicine | pmid:23219337 |
| Wang CZ et al. | Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. | 2013 | Int. J. Oncol. | pmid:23337959 |
| Kim TW et al. | Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity. | 2013 | Planta Med. | pmid:23818268 |
| Lin CC et al. | Wogonin, a natural and biologically-active flavonoid, influences a murine WEHI-3 leukemia model in vivo through enhancing populations of T- and B-cells. | 2013 Nov-Dec | In Vivo | pmid:24292576 |
| Xiao JR et al. | Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders. | 2014 | J Ocul Pharmacol Ther | pmid:25280175 |
| Wang H et al. | Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. | 2014 | Mol. Carcinog. | pmid:23761018 |
| Huang KF et al. | [Experimental study on inhibitory effect of wogonin on proliferation and invasion of breast cancer cells]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:25039187 |
| Shin HS et al. | Skullcap (Scutellaria baicalensis) extract and its active compound, wogonin, inhibit ovalbumin-induced Th2-mediated response. | 2014 | Molecules | pmid:24566319 |
| Marsh Z et al. | Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. | 2014 | Phytochemistry | pmid:25236693 |
| Yan T et al. | Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells. | 2014 | Diagn Pathol | pmid:25432585 |
| Zhao K et al. | Wogonin suppresses melanoma cell B16-F10 invasion and migration by inhibiting Ras-medicated pathways. | 2014 | PLoS ONE | pmid:25203554 |
| Yang H et al. | Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells. | 2014 | Oncotarget | pmid:25149543 |
| Yao J et al. | NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis. | 2014 | Cell Death Dis | pmid:24901054 |
| Xu X et al. | Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway. | 2014 | Biochem. Pharmacol. | pmid:25264278 |