| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sonoda M et al. | Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. | 2004 | J Ethnopharmacol | pmid:15036470 |
| Tian J et al. | Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA. | 2004 | J. Photochem. Photobiol. B, Biol. | pmid:15043845 |
| Woźniak D et al. | Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. | 2004 | Nahrung | pmid:15053344 |
| Dao TT et al. | Synthesis and biological activities of 8-arylflavones. | 2004 | Arch. Pharm. Res. | pmid:15089030 |
| Scuro LS et al. | Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation. | 2004 | BMC Biochem. | pmid:15102332 |
| Park S et al. | Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats. | 2004 | Dig. Dis. Sci. | pmid:15139485 |
| Lim H et al. | Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. | 2004 | Arch. Pharm. Res. | pmid:15180311 |
| Son D et al. | Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. | 2004 | Eur. J. Pharmacol. | pmid:15189769 |
| Murch SJ et al. | A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds. | 2004 | Plant Cell Rep. | pmid:15449017 |
| Cho J and Lee HK | Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. | 2004 | Biol. Pharm. Bull. | pmid:15467195 |
| Ong ES et al. | Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15468106 |
| Piao HZ et al. | Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. | 2004 | Arch. Pharm. Res. | pmid:15473663 |
| Li HB et al. | Separation methods used for Scutellaria baicalensis active components. | 2004 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15556504 |
| Chi YS and Kim HP | Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15589400 |
| Lim BO | Efficacy of wogonin in the production of immunoglobulins and cytokines by mesenteric lymph node lymphocytes in mouse colitis induced with dextran sulfate sodium. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15618621 |
| Ma Z et al. | Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. | 2005 | Blood | pmid:15626742 |
| Li C et al. | Non-aqueous capillary electrophoresis for simultaneous separation and determination of three major active components in traditional medicinal preparations. | 2005 | Biomed. Chromatogr. | pmid:15627280 |
| Ohtake N et al. | The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. | 2005 | Eur. J. Pharmacol. | pmid:15659321 |
| Chun W et al. | Synthetic wogonin derivatives suppress lipopolysaccharide-induced nitric oxide production and hydrogen peroxide-induced cytotoxicity. | 2005 | Arch. Pharm. Res. | pmid:15789754 |
| Yu CS et al. | Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. | 2005 Jan-Feb | Anticancer Res. | pmid:15816529 |
| Bonham M et al. | Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. | 2005 | Clin. Cancer Res. | pmid:15897592 |
| Tian J et al. | Interaction of wogonin with bovine serum albumin. | 2005 | Bioorg. Med. Chem. | pmid:15911327 |
| Chuang HN et al. | Enhancing effects of Scutellaria baicalensis and some of its constituents on TGF-beta1 gene expression in RAW 264.7 murine macrophage cell line. | 2005 | Planta Med. | pmid:15931583 |
| Li HB and Chen F | Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. | 2005 | J Chromatogr A | pmid:15941045 |
| Park H et al. | Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives. | 2005 | Eur J Med Chem | pmid:15963606 |
| Tai MC et al. | Therapeutic potential of wogonin: a naturally occurring flavonoid. | 2005 | CNS Drug Rev | pmid:16007236 |
| Dao TT et al. | Synthesis and iNOS inhibitory activities of thioflavones. | 2005 | Arch. Pharm. Res. | pmid:16042072 |
| Han CK et al. | Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism. | 2005 | Biol. Pharm. Bull. | pmid:16079475 |
| Hardeland R and Pandi-Perumal SR | Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. | 2005 | Nutr Metab (Lond) | pmid:16153306 |
| Jang J et al. | Structure and antiinflammatory activity relationships of wogonin derivatives. | 2005 | Arch. Pharm. Res. | pmid:16178410 |
| Park EJ et al. | Skullcapflavone I from Scutellaria baicalensis induces apoptosis in activated rat hepatic stellate cells. | 2005 | Planta Med. | pmid:16206047 |
| Goh D et al. | Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. | 2005 | J. Agric. Food Chem. | pmid:16218664 |
| Liu Y et al. | Binding of wogonin to human gammaglobulin. | 2005 | Int. J. Biol. Macromol. | pmid:16242767 |
| Yoon JH and Baek SJ | Molecular targets of dietary polyphenols with anti-inflammatory properties. | 2005 | Yonsei Med. J. | pmid:16259055 |
| Chang LC and Sun SW | Micellar electrokinetic chromatography for separation of a mixture of coptis alkaloids, scute flavonoids, and rhubarb anthraquinones and bianthrones. | 2006 | J Pharm Biomed Anal | pmid:16297588 |
| Zgórka G | Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus. | 2006 | J Chromatogr A | pmid:16364344 |
| Aung H et al. | Scutellaria baicalensis decreases ritonavir-induced nausea. | 2005 | AIDS Res Ther | pmid:16368007 |
| Du CF et al. | [Studies on chemical constituents in bark of dictamnus dasycarpus]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16400943 |
| Himeji M et al. | Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. | 2007 | Cancer Lett. | pmid:16497434 |
| Adams LS et al. | Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. | 2006 | Evid Based Complement Alternat Med | pmid:16550232 |
| Zhao Y et al. | Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. | 2006 | Eur. J. Pharmacol. | pmid:16574098 |
| Shen SC et al. | Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. | 2006 | Neuroscience | pmid:16580779 |
| Chang WT et al. | Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. | 2006 | Am. J. Chin. Med. | pmid:16700106 |
| Wang W et al. | The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo. | 2006 | Biol. Pharm. Bull. | pmid:16755005 |
| Feng YL et al. | [Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography]. | 2006 | Yao Xue Xue Bao | pmid:16759005 |
| Qu H et al. | Simultaneous determination of eight active components in Chinese medicine 'YIQING' capsule using high-performance liquid chromatography. | 2007 | J Pharm Biomed Anal | pmid:16846714 |
| Kim YH et al. | Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. | 2006 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:16893689 |
| Tang NY et al. | Effects of wogonin on the levels of cytokines and functions of leukocytes associated with NF-kappa B expression in Sprague-Dawley rats. | 2006 Jul-Aug | In Vivo | pmid:16900784 |
| Wang W et al. | Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. | 2006 | Anticancer Drugs | pmid:16926629 |
| Fas SC et al. | Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis. | 2006 | Blood | pmid:16931628 |