MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Wogonin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Penile Induration | D010411 | 4 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Neurodegenerative Diseases | D019636 | 32 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen M et al. | Simultaneous determination of wogonin, oroxylin a, schisandrin, paeoniflorin and emodin in rat serum by HPLC-MS/MS and application to pharmacokinetic studies. | 2017 | Biomed. Chromatogr. | pmid:28236316 |
Paudel MK et al. | An overview and comparison of a recombinant antigen-binding fragment and an antigen-binding fragment from a monoclonal antibody against wogonin glucuronide. | 2017 | J Nat Med | pmid:28623444 |
Chen J et al. | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Biomed. Pharmacother. | pmid:28486193 |
Shu Q et al. | Wogonin induces retinal neuron-like differentiation of bone marrow stem cells by inhibiting Notch-1 signaling. | 2017 | Oncotarget | pmid:28415701 |
Paudel MK et al. | The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide. | 2017 | J. Biotechnol. | pmid:28392422 |
Wu X et al. | Wogonin as a targeted therapeutic agent for EBV (+) lymphoma cells involved in LMP1/NF-κB/miR-155/PU.1 pathway. | 2017 | BMC Cancer | pmid:28222771 |
Khan NM et al. | Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes. | 2017 | Chem. Biol. Interact. | pmid:28688942 |
Wei CY et al. | Protective effect of wogonin on endotoxin-induced acute lung injury via reduction of p38 MAPK and JNK phosphorylation. | 2017 | Environ. Toxicol. | pmid:26892447 |
Bian J et al. | Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28117202 |
Lee HW et al. | Potent inhibition of monoamine oxidase A by decursin from Angelica gigas Nakai and by wogonin from Scutellaria baicalensis Georgi. | 2017 | Int. J. Biol. Macromol. | pmid:28109809 |