| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tian J et al. | A wogonin-loaded glycyrrhetinic acid-modified liposome for hepatic targeting with anti-tumor effects. | 2014 | Drug Deliv | pmid:24215357 |
| Si D et al. | Mechanism of CYP2C9 inhibition by flavones and flavonols. | 2009 | Drug Metab. Dispos. | pmid:19074529 |
| Yang T et al. | Wogonin enhances intracellular adiponectin levels and suppresses adiponectin secretion in 3T3-L1 adipocytes. | 2017 | Endocr. J. | pmid:27667474 |
| Yeh CH et al. | Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells. | 2014 | Environ. Toxicol. | pmid:23362215 |
| Wei CY et al. | Protective effect of wogonin on endotoxin-induced acute lung injury via reduction of p38 MAPK and JNK phosphorylation. | 2017 | Environ. Toxicol. | pmid:26892447 |
| Huang FM et al. | BisGMA-induced cytotoxicity and genotoxicity in macrophages are attenuated by wogonin via reduction of intrinsic caspase pathway activation. | 2016 | Environ. Toxicol. | pmid:26756871 |
| Sun HL et al. | Endotoxin-induced acute lung injury in mice is protected by 5,7-dihydroxy-8-methoxyflavone via inhibition of oxidative stress and HIF-1α. | 2016 | Environ. Toxicol. | pmid:26213241 |
| Boozari M et al. | Growth inhibition and apoptosis induction by Scutellaria pinnatifida A. Ham. on HL-60 and K562 leukemic cell lines. | 2015 | Environ. Toxicol. Pharmacol. | pmid:25546119 |
| Li T et al. | Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. | 2011 | Eur J Drug Metab Pharmacokinet | pmid:21713461 |
| Zhang Y et al. | The Influence of Compatibility of Rhubarb and Radix Scutellariae on the Pharmacokinetics of Anthraquinones and Flavonoids in Rat Plasma. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29134502 |
| Park H et al. | Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives. | 2005 | Eur J Med Chem | pmid:15963606 |
| Zhang F and Wang G | A review of non-nucleoside anti-hepatitis B virus agents. | 2014 | Eur J Med Chem | pmid:24549242 |
| Wang J et al. | Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro. | 2017 | Eur J Med Chem | pmid:28987604 |
| Sabra SA et al. | Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer. | 2018 | Eur J Pharm Biopharm | pmid:29689288 |
| Shao YX et al. | The molecular basis for the inhibition of human cytochrome P450 1A2 by oroxylin and wogonin. | 2012 | Eur. Biophys. J. | pmid:22228220 |
| Ono K et al. | Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. | 1990 | Eur. J. Biochem. | pmid:1695572 |
| Park HJ et al. | Induction of quinone reductase by a methanol extract of Scutellaria baicalensis and its flavonoids in murine Hepa 1c1c7 cells. | 1998 | Eur. J. Cancer Prev. | pmid:9926295 |
| Kimura Y and Sumiyoshi M | Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. | 2011 | Eur. J. Pharmacol. | pmid:21549115 |
| Ohtake N et al. | The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. | 2005 | Eur. J. Pharmacol. | pmid:15659321 |
| Park HG et al. | Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis. | 2007 | Eur. J. Pharmacol. | pmid:17692312 |