Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Brain Ischemia D002545 89 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Gastritis D005756 27 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Guo Q et al. Anti-hepatitis B virus activity of wogonin in vitro and in vivo. 2007 Antiviral Res. pmid:17280723
Yang L et al. Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins. 2013 Apoptosis pmid:23371323
Kim EH et al. Targeting Nrf2 with wogonin overcomes cisplatin resistance in head and neck cancer. 2016 Apoptosis pmid:27544755
Ku SK et al. Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. 2015 Arch. Pharm. Res. pmid:25564337
Dao TT et al. Synthesis and biological activities of 8-arylflavones. 2004 Arch. Pharm. Res. pmid:15089030
Dao TT et al. Synthesis and iNOS inhibitory activities of thioflavones. 2005 Arch. Pharm. Res. pmid:16042072
Jang J et al. Structure and antiinflammatory activity relationships of wogonin derivatives. 2005 Arch. Pharm. Res. pmid:16178410
Lim H et al. Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. 2004 Arch. Pharm. Res. pmid:15180311
Gurung SK et al. Inhibition of prostaglandin E2 production by synthetic wogonin analogs. 2009 Arch. Pharm. Res. pmid:20091262
Piao HZ et al. Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. 2004 Arch. Pharm. Res. pmid:15473663