Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Brain Ischemia D002545 89 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Gastritis D005756 27 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Ong ES et al. Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. 2004 Rapid Commun. Mass Spectrom. pmid:15468106
Piao HZ et al. Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. 2004 Arch. Pharm. Res. pmid:15473663
Li HB et al. Separation methods used for Scutellaria baicalensis active components. 2004 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15556504
Chi YS and Kim HP Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15589400
Lim BO Efficacy of wogonin in the production of immunoglobulins and cytokines by mesenteric lymph node lymphocytes in mouse colitis induced with dextran sulfate sodium. 2004 Biosci. Biotechnol. Biochem. pmid:15618621
Ma Z et al. Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. 2005 Blood pmid:15626742
Li C et al. Non-aqueous capillary electrophoresis for simultaneous separation and determination of three major active components in traditional medicinal preparations. 2005 Biomed. Chromatogr. pmid:15627280
Ohtake N et al. The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. 2005 Eur. J. Pharmacol. pmid:15659321
Chun W et al. Synthetic wogonin derivatives suppress lipopolysaccharide-induced nitric oxide production and hydrogen peroxide-induced cytotoxicity. 2005 Arch. Pharm. Res. pmid:15789754
Yu CS et al. Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. 2005 Jan-Feb Anticancer Res. pmid:15816529
Bonham M et al. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. 2005 Clin. Cancer Res. pmid:15897592
Tian J et al. Interaction of wogonin with bovine serum albumin. 2005 Bioorg. Med. Chem. pmid:15911327
Chuang HN et al. Enhancing effects of Scutellaria baicalensis and some of its constituents on TGF-beta1 gene expression in RAW 264.7 murine macrophage cell line. 2005 Planta Med. pmid:15931583
Li HB and Chen F Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. 2005 J Chromatogr A pmid:15941045
Park H et al. Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives. 2005 Eur J Med Chem pmid:15963606
Tai MC et al. Therapeutic potential of wogonin: a naturally occurring flavonoid. 2005 CNS Drug Rev pmid:16007236
Dao TT et al. Synthesis and iNOS inhibitory activities of thioflavones. 2005 Arch. Pharm. Res. pmid:16042072
Han CK et al. Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism. 2005 Biol. Pharm. Bull. pmid:16079475
Hardeland R and Pandi-Perumal SR Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. 2005 Nutr Metab (Lond) pmid:16153306
Jang J et al. Structure and antiinflammatory activity relationships of wogonin derivatives. 2005 Arch. Pharm. Res. pmid:16178410