Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Brain Ischemia D002545 89 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Gastritis D005756 27 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Zhao Q et al. A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis. 2016 Sci Adv pmid:27152350
Sun C et al. Rapid Isolation and Determination of Flavones in Biological Samples Using Zinc Complexation Coupled with High-Performance Liquid Chromatography. 2016 Molecules pmid:27537870
Fajol A et al. Fibroblast growth factor (Fgf) 23 gene transcription depends on actin cytoskeleton reorganization. 2016 FEBS Lett. pmid:26878191
Peng MX et al. Apoptotic Mechanism of Human Leukemia K562/A02 Cells Induced by Magnetic Ferroferric Oxide Nanoparticles Loaded with Wogonin. 2016 Chin. Med. J. pmid:27958228
Zhu N et al. Characterization and Bioavailability of Wogonin by Different Administration Routes in Beagles. 2016 Med. Sci. Monit. pmid:27744456
Zhang H et al. A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway. 2016 Int J Mol Sci pmid:27196894
Zhao L et al. LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells. 2016 Mol. Carcinog. pmid:25945460
Ku SK et al. Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. 2015 Arch. Pharm. Res. pmid:25564337
Woźniak D et al. Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix. 2015 Nat. Prod. Res. pmid:25427178
Liu J et al. Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression. 2015 PLoS ONE pmid:26317778
Ku SK and Bae JS Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. 2015 BMB Rep pmid:25739393
Qu JT et al. Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study. 2015 Biol. Pharm. Bull. pmid:26632179
Lu H et al. Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis. 2015 Mol Med Rep pmid:26398525
Zhang YM et al. Wogonin suppresses osteopontin expression in adipocytes by activating PPARα. 2015 Acta Pharmacol. Sin. pmid:26073326
Lee JY and Park W Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. 2015 Molecules pmid:25913928
Tan CX et al. Activities of wogonin analogs and other flavones against Flavobacterium columnare. 2015 Chem. Biodivers. pmid:25676507
Zhu Y and Wang J Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer's disease. 2015 Neurol. Sci. pmid:25596147
Boozari M et al. Growth inhibition and apoptosis induction by Scutellaria pinnatifida A. Ham. on HL-60 and K562 leukemic cell lines. 2015 Environ. Toxicol. Pharmacol. pmid:25546119
Chen S et al. Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway. 2015 Cell. Mol. Neurobiol. pmid:25504431
Chen F et al. Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway. 2015 J. Mol. Neurosci. pmid:25417142