Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Breast Neoplasms D001943 24 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Brain Ischemia D002545 89 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Gastritis D005756 27 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Tai MC et al. Therapeutic potential of wogonin: a naturally occurring flavonoid. 2005 CNS Drug Rev pmid:16007236
Li C et al. Non-aqueous capillary electrophoresis for simultaneous separation and determination of three major active components in traditional medicinal preparations. 2005 Biomed. Chromatogr. pmid:15627280
Yoon JH and Baek SJ Molecular targets of dietary polyphenols with anti-inflammatory properties. 2005 Yonsei Med. J. pmid:16259055
Aung H et al. Scutellaria baicalensis decreases ritonavir-induced nausea. 2005 AIDS Res Ther pmid:16368007
Dao TT et al. Synthesis and iNOS inhibitory activities of thioflavones. 2005 Arch. Pharm. Res. pmid:16042072
Hardeland R and Pandi-Perumal SR Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. 2005 Nutr Metab (Lond) pmid:16153306
Bonham M et al. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. 2005 Clin. Cancer Res. pmid:15897592
Park H et al. Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives. 2005 Eur J Med Chem pmid:15963606
Park EJ et al. Skullcapflavone I from Scutellaria baicalensis induces apoptosis in activated rat hepatic stellate cells. 2005 Planta Med. pmid:16206047
Jang J et al. Structure and antiinflammatory activity relationships of wogonin derivatives. 2005 Arch. Pharm. Res. pmid:16178410
Han CK et al. Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism. 2005 Biol. Pharm. Bull. pmid:16079475
Ma Z et al. Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. 2005 Blood pmid:15626742
Goh D et al. Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. 2005 J. Agric. Food Chem. pmid:16218664
Li HB and Chen F Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. 2005 J Chromatogr A pmid:15941045
Ohtake N et al. The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. 2005 Eur. J. Pharmacol. pmid:15659321
Yu CS et al. Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. 2005 Jan-Feb Anticancer Res. pmid:15816529
Lin CM et al. Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1. 2006 Int. Immunopharmacol. pmid:16979123
Wang W et al. Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. 2006 Anticancer Drugs pmid:16926629
Hu Y et al. Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. 2006 Biochem. Biophys. Res. Commun. pmid:17069758
Zhang H et al. Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. 2006 J Chromatogr A pmid:16952364